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COEXISTENCE OF PEPTIDES AND NEUROTRANSMITTERS

COEXISTENCE OF PEPTIDES AND NEUROTRANSMITTERS
肽和神经递质的共存
批准号:
3880836
负责人:
D M JACOBOWITZ
金额:
$0.0万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至

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中文摘要
翻译
脑桥背侧被盖神经元表达的区域分布 采用原位杂交技术检测大鼠肝组织中CCK信使RNA(MRNA)的表达 杂交组织化学技术。神经元的分布 在三叉神经运动核内观察到CCK基因的表达 神经的一个区域,还没有被证明含有CCK 免疫细胞化学方法。此外,CCK基因在尾部也有表达。 中缝背核与PREER相关的部分 免疫细胞化学观察。血管内皮细胞CCK基因表达的研究 胆碱能三叉神经运动核提示这些细胞表达 CCK基因,在以往的免疫细胞化学研究中未被检测到。 也提示CCK可能对肌肉收缩有影响。 三叉神经支配部位(如咀嚼肌)。
英文摘要
The regional distribution of dorsal pontine tegmental neurons expressing cholecystokinin (CCK) messenger RNA (mRNA) was examined using in situ hybridization histochemical techniques. A distribution of neurons containing CCK mRNA was observed in the motor nucleus of the trigeminal nerve a region which has not been shown to contain CCK by immunocytochemical means. In addition, CCK mRNA was seen in the caudal portion of the dorsal raphe nucleus which correlates with prior immunocytochemical observations. The presence of CCK mRNA in the cholinergic motor trigeminal nucleus suggests that these cells express the CCK gene which have gone undetected in previous immunocytochemical studies. It is also suggested that CCK may have an influence on muscular contraction at sites of trigeminal nerve innervation (e.g., muscles of mastication).
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LOCALIZATION AND CHARACTERIZATION OF BRAIN NEUROPEPTIDES
STUDIES OF CALRETININ IN PERIPHERAL ORGANS AND CELLS
COEXISTENCE OF PEPTIDES AND NEUROTRANSMITTERS
AUTOIMMUNE ASPECTS OF DISEASE
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