IMAGE PROCESSING OF ELECTRON MICROGRAPHS

电子显微照片的图像处理

• 批准号: 3916958
• 负责人: B L TRUS
• 金额: --
• 依托单位: CENTER FOR INFORMATION TECHNOLOGY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3916958
• 关键词: artificial intelligence; chemical structure; computer graphics /printing; computer simulation; computer system design /evaluation; cytoskeleton; electron microscopy; histopathology; image processing; intermediate filaments; liver; mathematical model; muscle proteins; statistics /biometry; striated muscles

This project facilitates structure determination from electron microscopy. Suitable software, hardware, and scientific expertise has been provided to allow other scientists, primarily at NIH, to use image processing and computer reconstruction to determine or understand a specimen's structure. Types of data analyzed include intermediate filaments, thin sections of both frozen hydrated myofilament of skeletal muscle and conventional stained embedded muscle, and liver coated vesicles. In addition, we are developing computer algorithms to unwrap images, produce radial density profiles, and perform various statistical and mathematical analyses of our image data.

该项目有助于根据电子确定结构。 显微镜。适合的软件、硬件和科学专业知识 已经提供给其他科学家，主要是NIH的科学家 使用图像处理和计算机重建来确定或 了解样本的结构。分析的数据类型包括 中间长丝，冰冻水合的薄片 骨骼肌肌丝和常规染色包埋 肌肉和肝脏包被的囊泡。此外，我们正在开发 计算机算法解开图像，产生径向密度 配置文件，并执行各种统计和数学分析 我们的图像数据。