VIRUS STRUCTURE AS DETERMINED BY IMAGE PROCESSING OF ELECTRON MICROGRAPHS

通过电子显微照片的图像处理确定病毒结构

• 批准号: 3963616
• 负责人: B L TRUS
• 金额: --
• 依托单位: CENTER FOR INFORMATION TECHNOLOGY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3963616
• 关键词: Vesiculovirus; bacteriophage T7; electron microscopy; image processing; scanning electron microscopy; virus envelope

Two new virus structures have been completed using image processing techniques developed in this laboratory. The high resolution structure of the herpes simplex virus has been determined (with NIDDK and USUHS). In addition, tail fibers of bacteriophage T7 have been analyzed (with NIDDK, NCI, and Brookhaven National Laboratory). These analyses have been successful in part as a result of new software that has been developed for correlation averaging of single particles (with BEIB and NIDDK).

两个新的病毒结构已完成使用图像处理 这个实验室开发的技术。 的高分辨率结构 单纯疱疹病毒已经确定（与NIDDK和USUHS）。 在 此外，已经分析了噬菌体T7的尾纤维（用NIDDK， NCI和Brookhaven国家实验室）。 这些分析是 成功的部分原因是新的软件已经开发， 单粒子的相关平均（使用BEIB和NIDDK）。