课题基金 / 基金详情

STUDIES OF THE NATURAL HISTORY AND TREATMENT OF DUCK HEPATITIS B VIRUS INFECTION

STUDIES OF THE NATURAL HISTORY AND TREATMENT OF DUCK HEPATITIS B VIRUS INFECTION
鸭乙型肝炎病毒感染自然史及治疗的研究
批准号：
3918255
负责人：
E A JONES
金额：
$0.0万
依托单位：
NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3918255
关键词：
antiviral agents chronic disease /disorder disease /disorder model duck hepatitis B virus ducks hepatitis B immunopharmacology liver disorder chemotherapy liver neoplasms medical complication virus replication

项目摘要

项目成果

E A JONES的其他基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
There are many similarities in structure and properties between the human hepatitis B virus (HBV) and the duck hepatitis B virus (DHBV). These similarities suggest that DHBV infection in ducks may be a useful experimental model of human HBV infection, particularly as HBV cannot be grown readily in cell culture. Ducks infected with DHBV at birth become chronic carriers of the virus, although they may not develop overt hepatitis. Some DHBV-infected ducks have been reported to develop hepatocellular carcinoma, a tumor strongly linked etiologically in humans with chronic hepatitis B infection. As a screening test for new effective therapies for chronic type B hepatitis in man, new antiviral immunomodulatory agents are being assessed for their ability to suppress DHBV replication in ducks.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
STUDIES OF THE OPIATE SYSTEM IN CHOLESTATIC LIVER DISEASE
TRIALS OF THERAPIES FOR PRIMARY BILLIARY CIRRHOSIS
STUDIES OF THE NATURAL HISTORY AND TREATMENT OF DUCK HEPATITIS B VIRUS INFECTION
NATURAL HISTORY AND TREATMENT OF CHRONIC NON-A, NON-B HEPATITIS