PREDICTIVE VALUE OF THE EEG IN FEBRILE SEIZURES

脑电图对热性惊厥的预测价值

• 批准号: 3922534
• 负责人: S E EMOTO
• 金额: --
• 依托单位: NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3922534
• 关键词: Bosnia-Hercegovina; child (0-11); diagnosis design /evaluation; electroencephalography; febrile seizure; human subject; information systems; longitudinal human study; prognosis; relapse /recurrence; statistics /biometry

This population based study will evaluate the significance of the EEG as a predictor for recurrence of seizures in those children who have had a simple febrile convulsion. Outcomes reported are febrile seizure recurrence and afebrile seizure occurrence. The evolution of the EEG pattern will be described, and patterns will be correlated with the clinical outcome. The clinical study is being carried out in Skopje, Yugoslavia, at the Pediatric Clinic of the University of Skopje. The study began in FY 1982 and final follow-up visits will be completed in FY 1988. Patient accrual was completed in December 1984, by which time approximately 400 patients with a febrile seizure, no prior complex or multiple seizures and with a normal or nonspecific abnormal EEG, were registered into the study and began the study protocol and follow-up. An additional 200 patients with a specific abnormal EEG were entered for baseline information and follow-up. Data editing and file creation are continuing. Statistical analysis of baseline EEG and its association with characteristics of the child and the clinical characteristics of the seizure is presently being conducted. The master file, including follow-up data at all visits for all patients, should be completed in FY 1989, at which time further analyses will be undertaken.

这项基于人群的研究将评估 脑电图可作为癫痫复发的预测因子， 有一个简单的热性惊厥。 报告的结局为 热性惊厥复发和无热性惊厥发生。 的 将描述EEG模式的演变，并且模式将 与临床结果相关。 临床研究正在南斯拉夫的斯科普里进行， 斯科普里大学儿科诊所。 该研究于1982财年开始，最终随访访视将于 1988年完成。 患者招募于12月完成 1984年，大约有400名发热患者 癫痫发作，没有先前的复杂或多发性癫痫发作，并与正常 或非特异性异常脑电图，登记到研究中， 开始研究方案和随访。 新增200名患者 具有特定异常EEG的患者输入基线信息 和后续行动。 数据编辑和文件创建正在继续。 基线EEG的统计分析及其与 儿童的特点和临床特点 检获的毒品现仍在进行中。 主文件， 包括所有患者在所有访视时的随访数据， 1989年完成，届时将进一步分析 进行。