PREDICTIVE VALUE OF THE EEG IN FEBRILE SEIZURES

脑电图对热性惊厥的预测价值

• 批准号: 3945242
• 负责人: S E EMOTO
• 金额: --
• 依托单位: NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3945242
• 关键词: Bosnia-Hercegovina; child (0-11); electroencephalography; febrile seizure; human subject; information systems; longitudinal human study; prognosis; relapse /recurrence

This population based study will evaluate the significance of the EEG as a predictor for recurrence of seizures in those children who have had a simple febrile convulsion. Outcome with respect to febrile seizure recurrence and afebrile seizure occurrence will be reported. The evolution of the EEG pattern will be described, and patterns will be correlated with the clinical outcome. The clinical study is being carried out in Skopje, Yugoslavia, at the Pediatric Clinic of the University of Skopje. The study began in FY '82 and will be completed in FY '88. Patient accrual was completed in December, 1984, by which time approximately 400 patients with a febrile seizure, no prior complex or multiple seizures and with a normal or nonspecific abnormal EEG, were registered into the study and began the study protocol and follow-up. An additional 300 patients with a specific abnormal EEG were entered for baseline information and follow- up. Data monitoring, editing and file creation are continuing. Statistical analysis of baseline EEG and its association with characteristics of the child and the clinical characteristics of the seizure began in FY '87. Follow-up should be completed on all patients by FY '88.

这项基于人群的研究将评估 脑电图作为儿童癫痫复发的预测指标 有过简单的热性惊厥 尊重的结果 对热性惊厥的复发和无热性惊厥的发生将 被举报。 将描述EEG模式的演变， 并且模式将与临床结果相关。 的 临床研究正在南斯拉夫的斯科普里进行， 斯科普里大学儿科诊所。 这项研究于1982财政年度开始，将于1988财政年度完成。 患者招募于1984年12月完成， 约400例发热性惊厥患者，既往无 复杂或多发性癫痫发作，并伴有正常或非特异性 异常脑电图，被登记到研究中，并开始研究 协议和后续行动。 另外300名患有特定 将异常EEG输入基线信息，并进行随访- 起来 数据监测、编辑和文件创建工作仍在继续。 基线EEG的统计分析及其与 儿童的特点和临床特点， 从87财政年度开始没收 应完成对所有 88年的病人。