FIBER OPTIC PROBES

需要一种合适的装置来直接测量氧气 血液和组织中的分压（pO2）， 研究应用。 目前可用的测量方法 pO2缺乏方便性、可靠性、速度和适用性， 感兴趣的情况。 开发电传感器的努力 没有成功。 理想的是具有非常小的pO2 可以插入血管或组织中的传感器 干扰小，可提供即时pO2监测 无论是短期还是长期。一种光纤传感器 对于这种应用是理想的，其优点是， 使用，非常小的尺寸和灵活性，安全性和低成本。 一 本文介绍了一种新型的pO2传感器， 氧的荧光猝灭。 传感器的可行性 其令人满意的性能已在 前几年的体外和体内试验。 的发展 传感器作为针探头已经完成。

A suitable device is needed for the direct measurement of oxygen partial pressure (pO2) in blood and tissue for both clinical and research applications. Methods currently available for measuring pO2 lack convenience, reliability, speed, and applicability to many situations of interest. Efforts to develop electrical sensors have not been successful. It is desirable to have a very small pO2 sensor which can be inserted into a blood vessel or tissue with little disturbance, that will provide instantaneous pO2 monitoring for either short or extended periods of time. A fiber-optic sensor is ideal for this application, with the advantage, for physiological use, of very small size and flexibility, safety, and low cost. A pO2 sensor has been developed, based upon the principle of fluorescence quenching by oxygen. The feasibility of the sensor and its satisfactory performance have been demonstrated in in vitro and in vivo tests in preceding years. The development of the sensor as a needle probe has been accomplished.