PATHOGENESIS OF CILIA-ASSOCIATED RESPIRATORY (CAR) BACILLUS INFECTIONS

纤毛相关呼吸道（CAR）芽孢杆菌感染的发病机制

• 批准号: 3978276
• 负责人: K S WAGGIE
• 金额: --
• 依托单位: DIVISION OF RESEARCH SERVICES
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3978276
• 关键词: Bacillus; bacterial disease; chronic disease /disorder; communicable diseases; respiratory disorder; respiratory disorder epidemiology; respiratory infections

The cilia-associated respiratory bacillus was first demonstrated with silver stains of sections of the respiratory tract of rats by workers in the Netherlands. It was isolated in embryonated hen's eggs by staff of Comparative Pathology Section (Inf. and Immun., Feb. 1985) as a result of efforts to diagnose and characterize chronic respiratory disease in rats from an investigator's lab at NIH. To date the agent has not been grown on cell free media. Because of its gliding, flexing motion in the absence of evidence of means of locomotion, it is believed to be a member of the group of gliding bacteria. Preliminary pathology studies indicate that infections in rats result in chronic respiratory disease.

纤毛相关呼吸杆菌首次被证实为 作业人员对大鼠呼吸道切片银染的观察 荷兰。它是由工作人员从鸡胚中分离出来的 比较病理科(参考和Immun，1985年2月) 大鼠慢性呼吸道疾病的诊断和特征研究进展 来自美国国立卫生研究院的一个调查实验室。到目前为止，代理商还没有成长起来 无细胞介质。因为它在没有滑行的情况下可以滑动、弯曲运动 移动方式的证据，它被认为是该组织的成员 会滑行的细菌。初步的病理学研究表明 老鼠的感染会导致慢性呼吸道疾病。