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DEVELOPMENT OF ENZYMES THAT INACTIVATE NEUROTOXIC AGENTS

DEVELOPMENT OF ENZYMES THAT INACTIVATE NEUROTOXIC AGENTS
灭活神经毒剂的酶的开发
批准号：
4696902
负责人：
R O BRADY
金额：
$0.0万
依托单位：
NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/4696902
关键词：
detoxification neurotoxins poison control soil microbiology

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中文摘要
翻译
一种降解巴比妥的酶已被鉴定并部分提纯 来自土壤微生物的萃取物。对以下各项的要求 最大催化活性正在测定中。我们试图扩大规模 这种酶的产生，以检验其在逆转 巴比妥致死量在毒理学实验中的影响 合适的动物。
英文摘要
An enzyme that degrades barbital has been identified and partially purified from extracts derived from a soil micro-organism. The requirements for maximal catalytic activity are being determined. We attempted to scale-up the production of this enzyme to examine its effectiveness in reversing the effects of lethal quantities of barbital in toxicological experiments with appropriate animals.
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会议论文
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