Life course methods and functional trajectories

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It is clear that both protective and adverse risk factors operate throughout life to cause disease and disability. But whether these factors are cumulative, or if their rate of change is particularly important, is still unclear. By understanding the trajectories of risk factors i.e how they operate across life and interact with each other, we can better identify periods in life which are particularly important to cause disease, and where interventions may have the greatest potential for benefit.