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HYPERANDROGENISM AS A RISK FACTOR FOR ATHEROGENESIS IN WOMEN WITH NIDDM

HYPERANDROGENISM AS A RISK FACTOR FOR ATHEROGENESIS IN WOMEN WITH NIDDM
雄激素过多症是 NIDDM 女性动脉粥样硬化的危险因素
批准号：
5218360
负责人：
MARY KORYTKOWSKI
金额：
$0.0万
依托单位：
--
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/5218360
关键词：
adrenal disorder androgens atherosclerosis clinical research diabetic angiopathy disease /disorder proneness /risk endocrine disorder estrogens female hormone regulation /control mechanism human subject noninsulin dependent diabetes mellitus postmenopause progesterone

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中文摘要
翻译
绝经后类型的心血管发病率和死亡率增加 II 糖尿病受试者。 本研究将评估以下假设： 增加，已知与循环脂质异常有关 与 1) 绝经后循环雄激素水平升高有关 2) 循环雄激素水平对葡萄糖给药的反应 糖尿病受试者和 3) 卵巢激素改变的影响 浓度。
英文摘要
Cardiovascular morbidity and mortality increase in post menopausal Type II diabetic subjects. This study will evaluate the hypothesis that this increase, known to be associated with circulating lipid abnormalities relates to 1) increased circulating androgen levels following menopause 2) circulating androgens levels in response to glucose administration in diabetic subjects and 3) the contribution of altered ovarian hormone concentrations.
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