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FAMPRIDINE THERAPY OF CHRONIC FIXED DEFICITS IN MULTIPLE SCLEROSIS

FAMPRIDINE THERAPY OF CHRONIC FIXED DEFICITS IN MULTIPLE SCLEROSIS
芬吡啶治疗多发性硬化症慢性固定性缺陷
批准号：
5224094
负责人：
Jerry Saul Wolinsky
金额：
$0.0万
依托单位：
--
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/5224094
关键词：
aminopyridines clinical research clinical trials drug screening /evaluation human subject human therapy evaluation multiple sclerosis nervous system disorder chemotherapy neurologic manifestations prognosis

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中文摘要
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英文摘要
Patients with clinically definite multiple sclerosis with moderate to moderately severe stable neurologic deficits will be randomized in this study to determine the efficacy and safety of various oral doses of fampridine. The primary study outcome is to determine the dose and serum levels at which neurologic improvement occurs with a sustained release formulation of fampridine. Primary analysis will focus on the proportion of patients achieving neurological improvement at each dose.
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会议论文
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