MODEL FOR CATALYTIC REDUCTIVE DEHALOGENATION

催化还原脱卤模型

• 批准号: 5211200
• 负责人: ROBERT Glenn ARNOLD
• 金额: --
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/5211200
• 关键词: anaerobiosis; bioreactors; biotransformation; carbon tetrachloride; catalyst; cell free system; cellular respiration; chlorohydrocarbon; detoxification; electrical potential; electrochemistry; electrodes; electron transport; environmental contamination; environmental engineering; environmental toxicology; halogenation; microorganism metabolism; organometallic compounds; photolysis; reducing agents; reduction; semiconduction; vitamin B12; waste treatment

This project is engineering oriented and investigates treatment technologies for heavily halogenated organic pollutants. These pollutants have generally proven to be resistant to aerobic biochemical treatment measures. Numerous investigators have recognized the potential advantages of reductive dehalogenation as a mechanism for pretreating such compounds for subsequent aerobic transformations. Staged treatments of this nature would eliminate potential hazards from the release of partially dehalogenated products of reductive processes. Both abiotic and biochemically driven reductive dehalogenation of chlorinated solvents are proposed for study and evaluation in this project. The abiotic and biochemical foci will be studied and developed via three model systems that promote dehalogenation of haloorganic compounds that would be applicable for use under field conditions. Proposed work includes: 1) fundamental and applied investigations into the use of semiconductor-macrocycle hybrid catalysts for the reductive dehalogenation of aqueous-phase halogenated organics; 2) parallel development of in situ groundwater treatment systems based on the use of zero-valence metals (Fe and zn) for the reductive dehalogenation of reductive targets; and 3) isolation and identification of the physiological elements responsible for the reductive dehalogenation of carbon tetrachloride by Shewanella putrefaciens 200.

该项目以工程为导向并调查治疗 大量卤代有机污染物的技术。 这些 通常证明污染物对有氧生化具有抗性 治疗措施。 许多调查人员已经意识到了潜力 还原脱征的优点作为预处理的机制 此类化合物用于随后的有氧转化。 分阶段治疗 这种性质将消除释放的潜在危害 减少过程的部分非启动产物。 都是非生物 和生化驱动的氯化溶剂还原性除盐 提出了该项目的研究和评估。 非生物和生化灶将通过三个研究和开发 促进卤代化合物除盐化的模型系统 适用于在现场条件下使用。 建议的工作 包括：1）对使用的基本和应用调查 半导体大环杂交催化剂，用于还原 水相卤化有机物的去回解； 2）平行 基于使用的原位地下水处理系统的开发 零价金（Fe和Zn）用于还原的脱卤 还原目标； 3）隔离和识别 负责还原性去盐的生理元素 Shewanella Putrefaciens 200。