MODEL FOR CATALYTIC REDUCTIVE DEHALOGENATION

催化还原脱卤模型

• 批准号: 6296570
• 负责人: ROBERT Glenn ARNOLD
• 金额: $ 12.65万
• 依托单位: UNIVERSITY OF ARIZONA
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-04-01 至 2000-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6296570
• 关键词: anaerobiosis; bioreactors; biotransformation; carbon tetrachloride; catalyst; cell free system; cellular respiration; chlorohydrocarbon; detoxification; electrical potential; electrochemistry; electrodes; electron transport; environmental contamination; environmental engineering; environmental toxicology; halogenation; microorganism metabolism; organometallic compounds; photolysis; reducing agents; reduction; semiconduction; vitamin B12; waste treatment

This project is engineering oriented and investigates treatment technologies for heavily halogenated organic pollutants. These pollutants have generally proven to be resistant to aerobic biochemical treatment measures. Numerous investigators have recognized the potential advantages of reductive dehalogenation as a mechanism for pretreating such compounds for subsequent aerobic transformations. Staged treatments of this nature would eliminate potential hazards from the release of partially dehalogenated products of reductive processes. Both abiotic and biochemically driven reductive dehalogenation of chlorinated solvents are proposed for study and evaluation in this project. The abiotic and biochemical foci will be studied and developed via three model systems that promote dehalogenation of haloorganic compounds that would be applicable for use under field conditions. Proposed work includes: 1) fundamental and applied investigations into the use of semiconductor-macrocycle hybrid catalysts for the reductive dehalogenation of aqueous-phase halogenated organics; 2) parallel development of in situ groundwater treatment systems based on the use of zero-valence metals (Fe and zn) for the reductive dehalogenation of reductive targets; and 3) isolation and identification of the physiological elements responsible for the reductive dehalogenation of carbon tetrachloride by Shewanella putrefaciens 200.

该项目以工程为导向，研究治理 治理重度卤化有机污染物的技术。这些 污染物通常已被证明对好氧生物化学具有抵抗力。 治疗措施。许多调查人员已经认识到了这种潜力 还原脱卤化作为一种预处理机制的优点 这样的化合物用于随后的有氧转化。分期治疗 这一性质将消除因释放 还原过程的部分脱卤化产物。都是非生物的 和生物化学驱动的氯化溶剂还原脱卤化 建议在本项目中研究和评估。 非生物和生化焦点将通过三个方面的研究和开发 促进卤代有机化合物脱卤化的模型系统 适用于野外条件下使用。建议的工作 包括：1)基础调查和应用调查 用于还原剂的半导体-大循环复合催化剂 水相卤化有机物的脱卤化；2)并行 基于可再生能源的地下水原位处理系统的开发 用于还原脱卤化的零价金属(铁和锌) 还原靶标；3)分离和鉴定 细菌还原脱卤化的生理因素 腐败希瓦氏杆菌200。