GCRF Partnership for Increasing the Impact of Vector Control (PIIVeC)

病媒传播的疾病普遍存在，造成大量发病率和死亡率，严重阻碍了整个发展中世界的经济发展。我们目前的许多工具在21世纪的城市环境中是不够的，或者由于杀虫剂耐药性而失效，而新的干预措施的证据基础仍然薄弱。选择最具成本效益、负担得起和可接受的工具来减轻病媒传播疾病的负担，需要采取一种综合办法，涉及病媒生物学家、经济学家和人类学家，并与国家卫生部、规划部和财政部合作。实际上，大多数疾病流行国家缺乏制定基于证据的战略来控制这些疾病的能力。病媒生物学家尤其严重短缺，但也迫切需要吸引其他学科的顶尖科学家来应对这一重大公共卫生危机。这项建议将建立一个伙伴关系，以增加病媒控制的影响。我们将汇集布基纳法索、喀麦隆和马拉维这三个病媒传播疾病负担特别高的非洲国家的主要研究机构和国家疾病控制规划，为病媒综合控制制定基于证据的解决办法。在LSTM的长期指导和对国内能力需求的严格评估的支持下，该伙伴关系将产生新的知识和工具，并加强国家决策，从而减少疾病负担，提高应对疫情的复原力。

Vector-borne diseases are pervasive, causing massive morbidity and mortality and severely retarding economic development across the developing world. Many of our current tools are inadequate in twenty first century urban environments or failing due to insecticide resistance, and the evidence base for newer interventions remains weak. Selecting the most cost effective, affordable and acceptable tools to reduce the burden of vector borne disease requires an integrated approach involving vector biologists, economists and anthropologists, working in partnership with national ministries of health, planning and finance. In reality, most disease endemic countries lack the capacity to develop evidence based strategies to control these diseases. There is a particularly acute shortage of vector biologists but also an urgent need to attract leading scientists from other disciplines to tackle this major public health crisis. This proposal will establish a Partnership to Increase the Impact of Vector Control. We will bring together leading research institutes and national disease control programmes from three African countries with exceptionally high burdens of vector borne disease, Burkina Faso, Cameroon and Malawi, to develop evidence based solutions for integrated vector control. Supported by long term mentorship from LSTM and rigorous evaluation of the capacity needs in-country, the Partnership will generate new knowledge and tools, and strengthen national decision-making leading to reduced disease burden and increased resilience for responding to outbreaks.