SUPERIONIC ELECTROPHYSIOLOGICAL SENSOR

描述：(逐字摘自申请者摘要)：电生理学 记录提供了廉价且非侵入性的人体监控 生理功能。有了我们的技术，密集的，一二八，二五六 电极可以在几分钟内使用，从而实现脑电 (EEG)在急诊和重症监护环境中记录。不幸的是，脑电波 在要求苛刻的临床环境中，录音经常被患者污染 运动，它通过人造的电化学信号 电解离子在电极表面的运动。这些运动伪像 可以最小化如果离子渗透膜插入之间 电极和皮肤-电解液界面。此第一阶段项目建议 一种新型运动最小化的上离子钠膜层流电极 人工制品，不需要皮肤磨损，并提供出色的电生理 录制以进行扩展监控。基于我们充满希望的试点数据，我们将 制作钠超离子导体(NASICON)的原型 上离子陶瓷与银-银结合的电极 氯化物电极表面。超级传感器的原型将是 在测地线传感器网络中与传统的银/氯化银电极交叉指， 并在各种条件下及以上进行脑电数据采集 不同的时间段来量化脑电质量和伪影抵抗 与常规记录的脑电数据相关的新传感器。 建议的商业应用：不可用

DESCRIPTION: (Verbatim from the Applicant's Abstract): Electrophysiologic recording provides inexpensive and non-invasive monitoring of human physiological function. With our technology, a dense array of 64, 128, or 256 electrodes can be applied in a few minutes, allowing electroencephalographic (EEG) recording in emergency and intensive care settings. Unfortunately, EEG recordings in demanding clinical settings are often contaminated by patient movement, which creates artifactural electrochemical signals through the movement of electrolytic ions at the electrode surface. These motion artifacts could be minimized if an ion-permeable membrane were interposed between the electrode and the skin-electrolyte interface. This Phase I project propose a novel superionic sodium membrane laminar electrode that would minimize motion artifacts, require no skin abrasion, and provide excellent electrophysiological recording for extended monitoring. Based on our promising pilot data, we will perform prototype fabrication of sodium superionic conducting (NASICON) electrodes in which the superionic ceramic is bonded to a silver-silver chloride electrode surface. The prototype superionic sensors will be interdigitated in the Geodesic Sensor Net with conventional Ag/AgCl electrodes, and EEG data acquisition will be conducted under various conditions and over varying periods of time to quantify the EEG quality and artifact resistance of new sensors in relation to EEG data from conventional recordings. PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE