VISUAL IMAGING OF BRAIN ELECTRICAL SIGNALS

密集传感器阵列技术的最新进展为以下方面开辟了道路： 人类大脑电场的新发现尽管源 定位方法可以揭示神经元中电场的来源， 组织，这些方法仍然高度推理。本项目将 开发先进的软件， 大脑在头部表面，借鉴工作站的最新发展， 图形和光学数据存储。通过密集的传感器阵列测量， 头表面字段可以精确指定，避免常见的 传统EEG绘图软件的插值误差。通过 用统计测量验证电子显示器， 可以建立成像过程的基础。拟议的第二阶段 实验将表征头部表面电位的关系 字段与引用无关的度量值，并将其与当前 密度场表示的拉普拉斯测度。表面成像计划 这个项目的成果将使大脑的精确成像 在头部表面的电场，提供了坚实的基础， 解剖学指定电源未来进展的测量 本地化 拟议的商业应用：常规EEG对头皮采样不足 电场，使得常规EEG脑映射可以产生 误导性的结果。Surface针对128通道和256通道阵列进行了优化， 成像程序可以证明是解释波形的有用辅助工具 数字脑电图在常规神经学实践中的应用。

Recent advances in dense sensor array technology have opened the way for new insights into human brain electrical fields. Although source localization methods may reveal the sources of electrical fields in neural tissue, these methods remain highly inferential. The present project would develop advanced software for imaging the electrical fields of the human brain at the head surface, drawing on recent developments in workstation graphics and optical data storage. With dense sensor array measurement, the head surface field may be specified with precision, avoiding the common errors of interpolation seen with conventional EEG mapping software. By validating the electrical display with statistical measures, an empirical basis for the imaging process may be established. The proposed Phase II experiments would characterize the relation of the head surface potential field with reference-independent measures, and contrast it with the current density field shown by Laplacian measures. The Surface Imaging Program resulting from this project would allow accurate imaging of brain electrical fields at the head surface, providing a solid basis in measurement for future advances in anatomically-specified electrical source localization. PROPOSED COMMERCIAL APPLICATION: Conventional EEG undersamples the scalp electrical field, such that conventional EEG brain mapping may produce misleading results. Optimized for 128- and 256-channel arrays, the Surface Imaging Program could prove a useful adjunct to interpreting waveform digital EEG in routine neurological practice.