SLOW, LATENT & TEMPERATE VIRUS INFECTIONS

在合同的病毒研究方面，研究工作的重点是确定美国及其在世界各地服役的军队的全国血液供应的安全性；动物源性食品的公共卫生安全性；以及开发和改进敏感和特定的诊断测试，这些测试将允许引入治疗方案，这些治疗方案将辐射疾病过程或阻止各种已知或怀疑会导致疾病的感染源的进展，这些疾病已被共同确定为传染性海绵状脑病(TSE)。承包商为分配给中枢神经系统研究实验室(NINDS)的非人类灵长类动物提供护理、住房和研究支持，以努力实现这些目标。承包商负责监测已经或将通过各种途径接种的非人类灵长类动物，这些灵长类动物的组织已知或怀疑感染了一种TSE制剂，记录结果，并执行适当的程序向项目官员提供动物样本进行评估。该合同的恒河猴繁殖方面的目标是开发一个恒河猴群体，能够为NINDS科学家提供不间断的特定年龄、无疾病的猕猴供应，以继续进行正在进行的研究项目并启动新的研究。

Research efforts concerning the viral study aspect of the contract are focused to determine the safety of the national blood supply in the United States and its military forces serving throughout the world; in the public health safety of animal derived food products; and the development and improvement of sensitive and specific diagnostic tests which will permit the introduction of therapeutic regimens that will either radiate the disease process or block the progression of the various infectious agents known, or suspected, to result in disease that has collectively been identified as Transmissible Spongiform Encephalopathies (TSEs). The contractor provides care, housing, and research support for nonhuman primates assigned to the Laboratory of Central Nervous System Studies, NINDS, in their effort to accomplish these goals. The contractor is responsible for monitoring nonhuman primates that have been, or will be, inoculated via various routes, with tissues known, or suspected to be, infected with one of the TSE agents, recording findings, and performing appropriate procedures to provide the Project Officer with animal samples for evaluation. The objective of the rhesus breeding aspect of the contract is to develop a colony of rhesus macaques capable of providing NINDS scientists with an uninterrupted supply of age-specific, disease-free macaques to continue on-going research projects and initiate new studies.