Use of dynamic network models to explore the role of social media use in HIV transmission and health promotion among gay men and other MSM

使用动态网络模型探讨社交媒体的使用在男同性恋者和其他 MSM 中艾滋病毒传播和健康促进中的作用

• 批准号: MR/S020462/2
• 负责人: Elizabeth Fearon
• 金额: $ 6.53万
• 依托单位: University College London
• 依托单位国家: 英国
• 项目类别: Fellowship
• 财政年份: 2023
• 资助国家: 英国
• 起止时间: 2023 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=MR%2FS020462%2F2
• 关键词: Use; dynamic; network; models; explore

The majority of HIV transmission takes place between individuals via sexual contacts. At a population level, these partnerships can be viewed as connected into a dynamic sexual partnership network, whose structural and compositional characteristics influence, and are influenced by, the HIV epidemic. Although this is well understood, lack of data and a framework for utilising sampled network data and strategies for translating simulation findings into health promotion strategies has prevented the use of data-driven dynamic network mathematical models to inform the design of interventions in specific settings. The way that individuals seek and form sexual partnerships is changing in many settings, and so plausibly are the characteristics of the sexual partnership network. A rapid rise in the use of online social media is occurring not only in high income settings, but also in sub-Saharan Africa. It is now both critical and feasible to develop a framework for data-driven dynamic partnership network models of HIV transmission, to understand the intersection of HIV acquisition and transmission risk with online socialising and partner-seeking, and to ensure that HIV prevention and engagement in care interventions can be most effectively designed and targeted.A key group affected by HIV across the world is men who have sex with men (MSM), including in sub-Saharan Africa (SSA). Studies of MSM in SSA have found high HIV prevalence and incidence, alongside widespread experience of social stigma, violence, harassment and poor access to sexual health services. The incentives for MSM to socialise and seek partners online are high, and correspondingly, there is great potential to use online social media venues to provide information or referrals for in-person HIV prevention, testing and care services. This project will use unique and current data on sexual partnerships, online and offline-initiated, HIV status and engagement in care, and social media use from representative samples of MSM from Nairobi and Johannesburg to develop dynamic network models of HIV transmission, explore the potential role of social media use in HIV transmission, and bring networks-based insight to improve targeting of health promotion and inform intervention development and future research to reduce HIV incidence.

大多数艾滋病毒传播是通过性接触在个人之间发生的。在人口一级，这些伙伴关系可被视为连接成一个动态的性伙伴关系网络，其结构和组成特点影响艾滋病毒流行病，并受艾滋病毒流行病的影响。虽然这是很好的理解，缺乏数据和框架，利用抽样网络数据和战略，将模拟结果转化为健康促进战略，阻止了使用数据驱动的动态网络数学模型，以通知在特定环境中的干预措施的设计。个人寻求和形成性伙伴关系的方式在许多环境中正在发生变化，性伙伴关系网络的特征也在发生变化。不仅在高收入环境中，而且在撒哈拉以南非洲，在线社交媒体的使用迅速增加。现在，为艾滋病毒传播的数据驱动的动态伙伴关系网络模型制定一个框架，了解艾滋病毒感染和传播风险与在线社交和寻找伙伴的交叉点，并确保艾滋病毒预防和参与护理干预措施能够最有效地设计和针对性，这既至关重要，也是可行的。包括撒哈拉以南非洲。对撒南非洲男男性行为者的研究发现，艾滋病毒流行率和发病率很高，同时普遍存在社会耻辱、暴力、骚扰和难以获得性健康服务的情况。男男性行为者在网上进行社交和寻找伴侣的动机很强，因此，利用网上社交媒体场所提供信息或转诊以获得面对面的艾滋病毒预防、检测和护理服务的潜力很大。该项目将利用来自内罗毕和约翰内斯堡的男男性行为者代表性样本的关于性伙伴关系、在线和离线发起的性伙伴关系、艾滋病毒状况和参与护理以及社交媒体使用的独特和最新数据，开发艾滋病毒传播的动态网络模型，探索社交媒体使用在艾滋病毒传播中的潜在作用，并带来基于网络的洞察力，以提高健康促进的针对性，并为干预措施的制定和未来的研究提供信息，以减少艾滋病毒的发病率。

项目成果

Accumulation of Immunity in Heavy-Tailed Sexual Contact Networks Shapes Mpox Outbreak Sizes.

• DOI: 10.1093/infdis/jiad254
• 发表时间: 2024-01-12
• 期刊: JOURNAL OF INFECTIOUS DISEASES
• 影响因子: 6.4
• 作者: Murayama, Hiroaki;Pearson, Carl A. B.;Abbott, Sam;Miura, Fuminari;Jung, Sung-mok;Fearon, Elizabeth;Funk, Sebastian;Endo, Akira
• 通讯作者: Endo, Akira

Improving modelling for epidemic responses: reflections from members of the UK infectious disease modelling community on their experiences during the COVID-19 pandemic

改进流行病应对模型：英国传染病模型界成员对他们在 COVID-19 大流行期间经历的反思

• DOI: 10.1101/2023.06.12.544667
• 发表时间: 2023
• 作者: Sherratt K