Exposure to particulate matter on the London Underground in healthy subjects and patients with chronic respiratory disease

健康受试者和患有慢性呼吸道疾病的患者在伦敦地铁上接触颗粒物

• 批准号: MR/S035613/1
• 负责人: Frank Kelly
• 金额: $ 114.53万
• 依托单位: Imperial College London
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2020
• 资助国家: 英国
• 起止时间: 2020 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=MR%2FS035613%2F1
• 关键词: Exposure; particulate; matter; London; Underground

Exposure to ambient air pollution - notably tiny particles called particulate matter (PM) - increases ill health and in some instances early death. There is no direct evidence of impacts on health from exposure to tunnel dust while travelling on the London Underground. However, this conclusion rests on a somewhat limited evidence base. Given that both long- and short-term exposure to ambient air pollutants is understood to be detrimental to health, it seems reasonable to assume that the same would be true of exposure to tunnel dust, when PM concentrations are much higher than those above ground. However, given the different physio-chemical properties of subway particles, compared with those found in ambient air, means that it is not currently possible to state the nature and extent of any health risk.In this study we will utilise a tried and tested approach to address the possible health impacts of the air in the London Underground. Using the same protocols as in our 'Oxford Street' studies we will investigate the health impacts of using the London underground network in healthy volunteers and subjects with cardio-respiratory problems.The outcome of this work will either provide assurance that the London underground air is safe to breathe and indicate that no further action is required to clean up the tube network or, alternatively, if health effects are found then this will support action for further cleaning up the underground environment. In these circumstances an improved underground environment will therefore benefit the health of all underground commuters.

暴露在环境空气污染中--尤其是被称为颗粒物(PM)的微小颗粒物--会增加健康状况，在某些情况下还会导致过早死亡。目前还没有直接证据表明，在伦敦地铁旅行时暴露在隧道粉尘中会对健康造成影响。然而，这一结论所依据的证据基础有些有限。考虑到长期和短期暴露在环境空气污染物中都被认为对健康有害，似乎有理由认为暴露在隧道粉尘中也是如此，因为PM浓度比地面上的浓度高得多。然而，由于地铁颗粒物的物理化学性质与环境空气中发现的不同，这意味着目前还不可能说明任何健康风险的性质和程度。在这项研究中，我们将使用一种经过试验和测试的方法来解决伦敦地铁空气可能对健康造成的影响。我们将使用与牛津大街研究相同的方案，调查使用伦敦地铁网络对健康志愿者和有心肺问题的受试者的健康影响。这项工作的结果将确保伦敦地下空气可以安全呼吸，并表明不需要采取进一步行动来清理管道网络，或者，如果发现对健康的影响，这将支持进一步清理地下环境的行动。因此，在这种情况下，改善地铁环境将有利于所有地铁通勤者的健康。

项目成果

Estimating the exposure-response function between long-term ozone exposure and under-5 mortality in 55 low-income and middle-income countries: a retrospective, multicentre, epidemiological study

估计 55 个低收入和中等收入国家长期臭氧暴露与 5 岁以下儿童死亡率之间的暴露-反应函数：一项回顾性、多中心、流行病学研究

• DOI: 10.1016/s2542-5196(23)00165-1
• 发表时间: 2023
• 期刊: The Lancet Planetary Health
• 作者: Xue T

Characterising a mobile reference station (MoRS) to quantify personal exposure to air quality

• DOI: 10.1016/j.atmosenv.2023.120160
• 发表时间: 2023-10
• 期刊: Atmospheric Environment
• 影响因子: 5
• 作者: M. Hedges;M. Priestman;M. Chadeau-Hyam;R. Sinharay;F. Kelly;David C. Green