NIEHS STATISTICAL CONSULTING SERVICE

NIEHS 统计咨询服务

• 批准号: 6106657
• 负责人: JOSEPH K HASEMAN
• 金额: --
• 依托单位: NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/6106657
• 关键词: health science research analysis /evaluation; neoplasm /cancer epidemiology; statistics /biometry; training

The Statistical Consulting Service was formally established in 1997 to provide a variety of experimental design and data analysis support to NIEHS research efforts. These activities range from brief consultations on experimental design and data analysis issues to more comprehensive collaborations that result in co-authorship of papers in subject matter journals. Approximately 80 NIEHS scientists, representing a number of different areas of environmental health research, made use of the Statistical Consulting Service this year. The list of publications that accompanies this project report provides more information as to the nature of these research collaborations, which include both laboratory and human studies. Specific examples of collaborative research activities involving the Statistical Consulting Service include an evaluation of reproductive tract carcinogenesis in a multi-generational study of DES, an investigation of the relationships among reproductive endpoints in Swiss mice, using the Reproductive Assessment by Continuous Breeding Database, the evaluation of rodent carcinogenicity in long term studies of 2,2-bis(bromomethyl)-1,3-propanediol, oxazepam, and isobutyraldehyde, and the collaborative development and characterization of the sisterhood design for studying the etiology of breast cancer, based on enrolling a "genetically enriched" cohort of sisters of cases in a prospective cohort design.

统计咨询服务处正式 成立于1997年，提供各种实验设计， 数据分析支持NIEHS研究工作。这些活动 范围从对实验设计和数据的简短咨询 分析问题，以更全面的合作，从而导致 在主题期刊上共同撰写论文。约 80名NIEHS科学家，代表了许多不同的领域， 环境卫生研究，利用统计 今年的咨询服务。出版物清单， 本项目报告所附的详细信息， 这些研究合作的性质，其中包括 实验室和人类研究。合作的具体例子 统计咨询处参与的研究活动 包括对一个生殖道致癌作用评价， DES的多代研究， 瑞士小鼠生殖终点之间的关系，使用 通过连续育种数据库进行的生殖评估， 长期研究中啮齿类动物致癌性的评价 2，2-双（溴甲基）-1，3-丙二醇，奥沙西泮，和 异丁醛，以及合作开发和 研究病因的姐妹关系设计的表征 乳腺癌，基于招募一个“基因丰富”的队列， 在一个前瞻性队列设计中的病例姐妹篇。