MENTAL RETARDATION AND DEVELOPMENTAL PSYCHOPATHOLOGY

此应用程序要求五年持续支持多 心理学研究的学科、生物学和心理学方案 发育迟缓与精神病理学。该计划强调 神经成熟、遗传和环境因素的相互作用 精神发育迟滞个体的产生及其自然过程 和发育障碍。该程序由一个共享的 理论视角、研究方法和研究策略。研究 还关注导致适应的进程和能力领域 关于特定残疾和双重诊断(精神发育迟滞+ 精神病理学)在明确的症状中。治疗研究是 提出了与基本的、基本的机制有关的建议。 四个研究项目领域主要集中在理论和 临床意义与认识和改善 智力低下与发育障碍：1)精神发育迟滞 在宫内接触毒品并在高危环境中成长的儿童 环境：2)抽动秽语综合征及相关障碍模型 了解发育过程中基因与环境的相互作用 3)神经心理和神经生物学分化 自闭症和阿斯伯格综合征；4)家庭和遗传影响 特定证候个体的发育轨迹研究 精神发育迟滞。 该计划由三个核心研究资源支持： 管理；评估；生物统计学和方法论。这些 核心提供最先进的协作和咨询。

This application requests five years of continued support for a multi- disciplinary, biological, and psychological program of research of Mental Retardation and Developmental Psychopathology. The Program emphasizes the interaction of neuro-maturational, genetic, and environmental factors in the emergence and natural course of individuals with mental retardation and developmental disorders. The program is unified by a shared theoretical perspective, methods, and research strategies. Studies concern processes leading to adaptation and areas of competence, as well as to specific disabilities and dual diagnosis (mental retardation + psychopathology) in well-defined syndromes. Treatment studies are proposed that relate to basic, underlying mechanisms. The four Research Project Areas focus on major domains of theoretical and clinical importance in relation to the understanding and amelioration of mental retardation and developmental disorders: 1) the development of children exposed to drugs in utero and growing up in high-risk environments: 2) Tourette's syndrome and associated disorders as models for understanding gene-environment interaction in developmental disorders; 3) neuropsychological and neurobiological differentiation of autism and Asperger's syndrome; and 4) familial and genetic influences on the developmental trajectories of individuals with specific syndromes of mental retardation. The program is supported by three Core Research Resources: Administration; Assessment; and Biostatistics and Methodology. These Cores provide state-of-the art collaboration and consultation.