DEVELOPMENTAL CONTINUITY OF INDIVIDUAL DIFFERENCES IN REACTIVITY IN MONKEYS

这个项目研究灵长类生物行为。 恒河猴的纵向比较研究进展 和卷尾猴，特别强调 不同的行为和生理的个体模式 对环境新颖性和挑战的回应等 确定对个人的长期发展后果 不同的遗传背景，在不同的生理和 社会环境。在1997财年进行的研究(A) 确定了3个不同的典型行为反应簇 对一个月大的恒河猴婴儿的新颖性；(B)展示 年定向和运动能力的加速发展 苗圃饲养的恒河猴婴儿接受补充剂 他们的标准配方饮食中的必需脂肪酸从 出生；(C)表现出行为上的显著差异 母乳喂养恒河猴幼崽发育的研究 慢性脑脊液中5-HIAA的浓度不同， 中枢5-羟色胺的主要代谢物；(D)有记录的重要 自由放牧动物的求偶缺陷和生殖行为 恒河猴青春期和年轻成年雄性 慢性脑脊液5-HIAA浓度低；(E)描述系统性 不同类型肺炎的相对发病率之间的关系 攻击行为与脑脊液中5-HIAA和睾酮水平的关系 自由放养的成年雄性恒河猴；(F)特征为矮小- 以及不同早期阶段之间的长期预测关系 行为和活动状态配置文件以及随后的生物行为 卷尾猴幼体和幼体的发育轨迹 青少年；和(G)证明了 典型生物行为反应的个体差异 卷尾猴幼崽及其后代面临的挑战 倾向于探索性和原创性的工具使用行为。

This project investigates primate biobehavioral development through comparative longitudinal studies of rhesus and capuchin monkeys, with special emphasis on characterizing individual patterns of differential behavioral and physiological responses to environmental novelty and challenge and on determining long-term developmental consequences for individuals of different genetic backgrounds reared in different physical and social environments. Research carried out during FY97 (a) identified 3 distinctive clusters of prototypical behavioral response to novelty in month-old rhesus monkey infants; (b) demonstrated accelerated development of orienting and motor capabilities in nursery-reared rhesus monkey infants who received supplements of essential fatty acids to their standard formula diets beginning at birth; (c) characterized significant differences in behavioral development among rhesus monkey infants reared by mothers who differed systematically in chronic CSF concentrations of 5-HIAA, the primary central serotonin metabolite; (d) documented significant deficits in courtship and reproductive behavior in free-ranging rhesus monkey adolescent and young adult males with unusually low chronic CSF 5-HIAA concentrations; (e) decribed systematic associations between the relative incidence of different types of aggressive behavior and CSF levels of 5-HIAA and testosterone in free-ranging rhesus monkey adult males; (f) characterized short- and long-term predictive relationships between different early behavioral and activity state profiles and subsequent biobehavioral developmental trajectories in capuchin monkey infants and juveniles; and (g) demonstrated a predictive relationship between individual differences in prototypic biobehavioral response to challenge among capuchin monkey infants and their subsequent proclivity to engage in exploratory and proto-tool use behaviors.