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RADIATION FIELD MODELING AND COMPUTERIZED TREATMENT PLANNING

RADIATION FIELD MODELING AND COMPUTERIZED TREATMENT PLANNING
辐射场建模和计算机化治疗计划
批准号:
6123649
负责人:
R MILLER
金额:
$0.0万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至

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中文摘要
翻译
“医学成像和医疗技术的巨大进步 近年来的本地化技术给 物理和计算机技术来扩展 计算机化的治疗计划和优化。一种新的光子 使用由实验得出的卷积核的束流模型 已派生数据,并将其添加为以下TPS的替代方案 对照较旧的基于NFD的模型进行评估。数量 电子束模型中的综合扇区已增加 从16提高到128,极大地提高了不规则的精度 场剂量分布。治疗的下一次临床释放 计划系统已被推迟,以便纳入更多 改进。三个主要变化是:(1) 显卡驱动从8位到24位,从而完全适应 CT、MR和数字射线照相的动态范围以及 为了允许器官的透明阴影,这是一种刚刚 可与当前的PPC 604代处理器一起使用; (2)识别用户提供的治疗机数据,而不是 目前仅适用于一家机构的硬编码数据; 以及(3)将电子束算法扩展到三 具有同质性校正的尺寸,而不是2-D单位 目前正在使用的密度模型。此版本计划在晚些时候发布 1998年春天。目前的研究版本已经包含了 对比治疗计划,并排显示 相对较热和较冷的区域,显示屏采用标准的512 x 512主窗口,具有较小的辅助窗口。主 图像可以平移和缩放,以精确地勾勒出较小的轮廓 结构。能够添加额外的“”插入式“”波束数据集 也将添加。协调的CT-MRI计划也是 介绍了使用一组工具来缩放和配准图像以及 以标准的TPS格式输出结果。一个单独的计划 用于使用AAPM进行计算的近距离放射治疗 TG-43形式主义。对角剂量和径向剂量的修改 已经制定了允许治疗计划的功能 血管内放射治疗。在98财年,一种商业治疗 将采购规划系统,以减轻 直接的临床支持。研究将继续进行,有可能 商业联合赞助。能够在两地之间移动 多层次图像和剂量分布,以及非轴视图 (光束的眼睛,矢状面,冠状面)使用键盘命令 极大地提高了该程序的临床实用性。
英文摘要
"The vast improvements of the medical imaging and localization technology over recent years has brought a challenge to physics and computer technology to extend the capabilities of computerized treatment planning and optimization. A new photon beam model using a convolution kernel derived from experimental data has been derived and added as an alternative to the TPS for evaluation against the older NFD-based model. The number of integrated sectors in the electron beam model has been increased from 16 to 128, considerably improving the accuracy of irregular field dose distributions. The next clinical release of the treatment planning system has been delayed in order to incorporate further improvements. The three major changes are (1) the extension of the graphics drivers from 8 bit to 24 bit, so as to accommodate the full dynamic range of both CT, MR and Digital radiography, as well as to permit transparancy shading of organs, a feature which has just become available with the current PPC 604 generation processors; (2) recognition of user-supplied treatment machine data, rather than the hard coded data which currently applies to only one institution; and (3) expansion of the electron beam algorithm to three dimensions with homogeneity correction, rather than the 2-D, unit density model currently in use. This release is scheduled for late Spring 1998. The current research version already incorporates comparative treatment planning, with side-by-side displays of relative hot and cold regions, the display features a standard 512 x 512 main window, with smaller secondary windows. The main image can be panned and zoomed for acurate outlining of small structures. The ability to add additional ""drop-in"" beam datasets will also be added. Coordinated CT-MRI planning was also introduced using a set of tools to scale and register images and output the results in the standard TPS format. A separate program for brachytherapy which performs calculations using the AAPM TG-43 formalism. Modifications to the angular and radial dose functions have been made to permit treatment planning for intravascular brachytherapy. In FY 98, a commercial treatment planning system will be procured to alleviate the responsibilities of direct clinical support. Research will continue, with possible commercial co-sponsorship. The ability to move between multi-level images and dose distributions, as well as non-axial views (beams' eye, sagittal, coronal) using keyboard commands has greatly improved the clinical utility of the program."
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PICOSECOND OPTICAL STUDIES IN PROTEINS
  • 批准号:
    3300391
  • 项目类别:
  • 资助金额:
    $9.93万
  • 财政年份:
    1989
  • 负责人:
    R MILLER
  • 依托单位:
PICOSECOND OPTICAL STUDIES IN PROTEINS
  • 批准号:
    3300390
  • 项目类别:
  • 资助金额:
    $8.64万
  • 财政年份:
    1989
  • 负责人:
    R MILLER
  • 依托单位:
RADIATION FIELD MODELING AND COMPUTERIZED TREATMENT PLANNING
RADIATION THERAPY WITH RADIOLABELLED ANTIBODIES--TECHNICAL ASPECTS AND DOSIMETRY
  • 批准号:
    3916597
  • 项目类别:
  • 资助金额:
    $0.0万
  • 财政年份:
    --
  • 负责人:
    R MILLER
  • 依托单位:
海外基金