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RADIATION FIELD MODELING AND COMPUTERIZED TREATMENT PLANNING

RADIATION FIELD MODELING AND COMPUTERIZED TREATMENT PLANNING
辐射场建模和计算机化治疗计划
批准号:
6123649
负责人:
R MILLER
金额:
$0.0万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至

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中文摘要
翻译
“医学成像的巨大进步, 近年来,本地化技术给 物理学和计算机技术,以扩展的能力, 计算机化治疗计划和优化。新的光子 使用来自实验的卷积核的梁模型 数据已被导出并添加为TPS的替代方案, 对旧的基于NFD的模型进行评估。的数量 在电子束模型中增加了集成扇区 从16到128,大大提高了不规则 射野剂量分布下一个临床版本的治疗 规划系统已被推迟,以纳入进一步 改进.三大变化是(1)延长 图形驱动程序从8位到24位,以适应完整的 CT、MR和数字X线摄影的动态范围,以及 允许器官的透明阴影,这是一个功能, 与当前的PPC 604代处理器一起使用; (2)识别用户提供的治疗机数据,而不是 目前只适用于一个机构的硬编码数据; 以及(3)将电子束算法扩展到三个 具有均匀性校正的尺寸,而不是二维单位 目前使用的密度模型。此版本定于晚些时候 1998年春。目前的研究版本已经纳入了 比较治疗计划,并排显示 在相对较热和较冷的区域,显示器具有标准的512 x 512主窗口,带有较小的辅助窗口。主要 图像可以平移和缩放,以精确描绘小 结构.添加附加““drop-in””射束数据集的功能 也将被添加。协调的CT-MRI计划也是 介绍了使用一组工具来缩放和配准图像, 以标准TPS格式输出结果。一个单独的程序 对于使用AAPM进行计算的近距离放射治疗 TG-43形式主义。角剂量和径向剂量的修改 已制定功能,以允许治疗计划, 血管内近距离放射治疗在1998财政年度, 将采购规划系统,以减轻 直接临床支持。研究将继续进行, 商业赞助。能够在 多级图像和剂量分布,以及非轴向视图 (光束的眼睛,矢状,冠状)使用键盘命令, 大大提高了该程序的临床实用性。"
英文摘要
"The vast improvements of the medical imaging and localization technology over recent years has brought a challenge to physics and computer technology to extend the capabilities of computerized treatment planning and optimization. A new photon beam model using a convolution kernel derived from experimental data has been derived and added as an alternative to the TPS for evaluation against the older NFD-based model. The number of integrated sectors in the electron beam model has been increased from 16 to 128, considerably improving the accuracy of irregular field dose distributions. The next clinical release of the treatment planning system has been delayed in order to incorporate further improvements. The three major changes are (1) the extension of the graphics drivers from 8 bit to 24 bit, so as to accommodate the full dynamic range of both CT, MR and Digital radiography, as well as to permit transparancy shading of organs, a feature which has just become available with the current PPC 604 generation processors; (2) recognition of user-supplied treatment machine data, rather than the hard coded data which currently applies to only one institution; and (3) expansion of the electron beam algorithm to three dimensions with homogeneity correction, rather than the 2-D, unit density model currently in use. This release is scheduled for late Spring 1998. The current research version already incorporates comparative treatment planning, with side-by-side displays of relative hot and cold regions, the display features a standard 512 x 512 main window, with smaller secondary windows. The main image can be panned and zoomed for acurate outlining of small structures. The ability to add additional ""drop-in"" beam datasets will also be added. Coordinated CT-MRI planning was also introduced using a set of tools to scale and register images and output the results in the standard TPS format. A separate program for brachytherapy which performs calculations using the AAPM TG-43 formalism. Modifications to the angular and radial dose functions have been made to permit treatment planning for intravascular brachytherapy. In FY 98, a commercial treatment planning system will be procured to alleviate the responsibilities of direct clinical support. Research will continue, with possible commercial co-sponsorship. The ability to move between multi-level images and dose distributions, as well as non-axial views (beams' eye, sagittal, coronal) using keyboard commands has greatly improved the clinical utility of the program."
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PICOSECOND OPTICAL STUDIES IN PROTEINS
  • 批准号:
    3300391
  • 项目类别:
  • 资助金额:
    $9.93万
  • 财政年份:
    1989
  • 负责人:
    R MILLER
  • 依托单位:
PICOSECOND OPTICAL STUDIES IN PROTEINS
  • 批准号:
    3300390
  • 项目类别:
  • 资助金额:
    $8.64万
  • 财政年份:
    1989
  • 负责人:
    R MILLER
  • 依托单位:
RADIATION THERAPY WITH RADIOLABELLED ANTIBODIES--TECHNICAL ASPECTS AND DOSIMETRY
  • 批准号:
    3916597
  • 项目类别:
  • 资助金额:
    $0.0万
  • 财政年份:
    --
  • 负责人:
    R MILLER
  • 依托单位:
RADIATION FIELD MODELING AND COMPUTERIZED TREATMENT PLANNING
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