Development of novel reagents for the point-of-care(field) diagnosis &differentiation of the malaria parasites, Plasmodi

开发用于现场诊断的新型试剂

• 批准号: nhmrc : 280634
• 负责人: Prof Leann Tilley
• 金额: $ 7.8万
• 依托单位: La Trobe University
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Development Grants
• 财政年份: 2004
• 资助国家: 澳大利亚
• 起止时间: 2004-01-01 至 2005-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/development-novel-reagents-parasites-plasmodi/77587
• 关键词: Development; novel; reagents; point; care

Malaria is a major global health problem. 500 million people become infected with malaria parasites every year and 2-3 million people die each year from the disease. Rapid diagnosis of the disease is needed to allow correct treatment protocols. Increasingly protein-based immunochromatographic tests are being employed for the diagnosis of malaria as they offer significant advantages over classical thick smear tests, which require trained personnel and laboratory facilities. We propose to develop a protein-based malaria diagnostic that has the ability to distinguish the two major human pathogens, P.falciparum and P. vivax.

疟疾是一个主要的全球健康问题。每年有5亿人感染疟疾寄生虫，每年有200万至300万人死于这种疾病。为了制定正确的治疗方案，需要对该病进行快速诊断。越来越多的基于蛋白质的免疫层析试验被用于疟疾的诊断，因为它们比传统的厚涂片试验具有显著的优势，后者需要训练有素的人员和实验室设施。我们建议开发一种基于蛋白质的疟疾诊断方法，能够区分两种主要的人类病原体，恶性疟原虫和间日疟原虫。