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4 MONTH BIOMED GRANT LETTER WAS SENT TO D DEERFIELD

4 MONTH BIOMED GRANT LETTER WAS SENT TO D DEERFIELD
4 个月的 Biomed 授权信已发送给 D DEERFIELD
批准号:
6221024
负责人:
Bernard MONTGOMERY PETTITT
金额:
$0.13万
依托单位国家:
美国
项目类别:
财政年份:
1999
资助国家:
美国
项目状态:
已结题
起止时间:
1999-08-01 至 2000-07-31

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中文摘要
翻译
这项研究的重点涉及分子分析。 原生动物对哺乳动物DNA和蛋白质序列的模仿 寄生虫,克氏锥虫。我们已经证明了这种寄生虫 基因组包含模仿宿主序列的DNA序列,并且 编码与宿主免疫调节功能相似的蛋白质 蛋白质。这些寄生虫蛋白帮助它在 哺乳动物的血液通过下调宿主的免疫反应 寄生虫。
英文摘要
The focus of this research involves the analysis of the molecular mimicry of mammalian DNA and protein sequences by the protozoan parasite, Trypanosoma cruzi. We have demonstrated that the parasite genome contains DNA sequences which mimic host sequences and which encode proteins with functional similarity to host immune regulatory proteins. These parasite proteins assist its survival in the mammalian bloodstream by down regulating the host immune response to the parasites.
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Acquisition of Unix Computer Cluster for Molecular Dynamics Simulation Calculations
The role of structural plasticity in the norovirus capsid
The role of structural plasticity in the norovirus capsid
SALT EFFECTS IN SOLUTIONS OF PEPTIDES AND NUCLEIC ACIDS
  • 批准号:
    8171817
  • 项目类别:
  • 资助金额:
    $0.11万
  • 财政年份:
    2010
  • 负责人:
    Bernard MONTGOMERY PETTITT
  • 依托单位:
海外基金