MEIOSIS GORDON CONFERENCE

描述（改编自申请人的描述）：减数分裂戈登 会议将于2000年6月18日至23日在纽约的科尔比-索耶学院举行。 伦敦，新罕布什尔州。 减数分裂时染色体分离不当 导致至少10%的人类妊娠染色体不平衡。 这 导致流产或出生缺陷，是精神疾病的主要原因。 在美国的延迟。 减数分裂的关键细胞过程， 例如重组、染色单体凝聚和细胞周期检查点控制， 在维持细胞基因组完整性方面也发挥着重要作用， 身体 特别是，这些过程修复DNA损伤， 染色体错误分离可能导致癌症。 因此， 了解减数分裂和减数分裂染色体分离的控制， 与确保人类正常发展和防止 导致瘤形成的异常生长。 减数分裂戈登会议将 为来自世界各地的科学家提供了一个聚会的机会， 讨论减数分裂。 约有130名科学家参加。 大多数与会者是 学术研究机构的主要研究人员，但博士后 研究员、研究生以及工业界和政府的成员 实验室也将参加。 将有大约40名特邀演讲者，他们 讲座将涵盖模式生物减数分裂的各个方面，以及在 人类 将提出一系列方法，包括细胞学， 遗传学细胞生物学和生物化学 全体会议将涵盖减数分裂 DNA复制和重组起始，重组生物化学和 机制，减数分裂前染色体联合，染色体结构和 联会，染色单体凝聚，染色体分离控制，减数分裂 进展和配子发生。 海报会议和讲习班也将 提供科学讨论和交流思想的机会。 的 减数分裂戈登会议是仅有的两个科学会议之一， 专注于减数分裂 另一次会议隔年举行， 欧洲，重点局限于染色体行为， 参与的机会，特别是来自美国的科学家 States. 除了是2000年举行的唯一一次关于减数分裂的会议外， 减数分裂戈登会议将涵盖减数分裂的所有方面，包括 细胞周期调控和配子发生。

DESCRIPTION (Adapted from applicant's description): The Meiosis Gordon Conference will be held June 18-23, 2000 at Colby-Sawyer College in New London, New Hampshire. Improper segregation of chromosomes during meiosis results in chromosome imbalance in at least 10% of human pregnancies. This causes miscarriage or birth defects, and is the leading cause of mental retardation in the United States. Cellular processes critical to meiosis, such as recombination, chromatid cohesion and cell cycle checkpoint control, also pay important roles in maintaining genome integrity in cells throughout the body. In particular, these processes repair DNA damage and prevent chromosome missegregation that might otherwise lead to cancer. Thus, an understanding of the control of meiosis and meiotic chromosome segregation is highly relevant for efforts to ensure normal human development and to prevent abnormal growth leading to neoplasia. The Meiosis Gordon conference will provide an opportunity for scientists from throughout the world to meet and discuss meiosis. About 130 scientists will participate. Most attendees are principal investigators at academic research institutions, but postdoctoral fellows, graduate students, and members of industrial and government laboratories will also attend. There will be about 40 invited speakers, whose lectures will cover all aspects of meiosis in model organisms as well as in humans. A range of approaches will be presented, including cytology, genetics, cell biology, and biochemistry. Plenary sessions will cover meiotic DNA replication and recombination initiation, recombination biochemistry and mechanisms, premeiotic chromosome association, chromosome structure and synapsis, chromatid cohesion, control of chromosome segregation, meiotic progression, and gametogenesis. Poster sessions and workshops will also provide opportunities for scientific discussion and exchange of ideas. The Meiosis Gordon Conference is one of only two scientific meetings that concentrate on meiosis. The other meeting is held in alternate years in Europe, with a focus restricted to chromosome behavior and a more limited opportunity for participation, especially for scientists from the United States. In addition to being the only meeting on meiosis to be held in 2000, the Meiosis Gordon Conference will cover all aspects of meiosis, including cell cycle regulation and gametogenesis.