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Mathematical models of experimental microbial evolution

Mathematical models of experimental microbial evolution
实验微生物进化的数学模型
批准号:
NE/E013007/3
负责人:
Ivana Gudelj
金额:
$15.14万
依托单位:
依托单位国家:
英国
项目类别:
Fellowship
财政年份:
2011
资助国家:
英国
项目状态:
已结题
起止时间:
2011 至 --

项目摘要

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中文摘要
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英文摘要
My research lies at the interface of ecology and evolution and is focused around two key questions in evolutionary ecology: 'What determines species diversity?' and 'How did cooperative behaviour evolve?' These questions are among 25 unsolved problems facing the scientific community over the coming decade highlighted in the 125th anniversary issue of Science. The Science issue also stressed that the advancement of our understanding of the issues relating to the above questions requires a 'major interdisciplinary' effort and this is precisely what my fellowship will address. The fellowship is a collaboration between myself as a mathematical modeller and a group of experimental microbial population biologists namely Dr A Buckling, University of Oxford; Dr T Ferenci, University of Sydney; Professor P Rainey, University of Auckland; and Dr C MacLean, Imperial College London. I will be based at the University of Bath where I will work on the development of mathematical models for a range of projects designed to explore ecological mechanisms involved in the evolution of diversity and cooperation. The studies will be conducted by bringing to bare modern techniques of mathematical analysis and computation on the microbial evolutionary experiments of my collaborators.
期刊论文(8)
专著(0)
科研奖励(0)
会议论文
Testing the optimality properties of a dual antibiotic treatment in a two-locus, two-allele model.
在双基因座、双等位基因模型中测试双抗生素治疗的最优特性。
DOI: 10.1098/rsif.2013.1035
发表时间: 2014
期刊: Journal of the Royal Society, Interface
影响因子: --
作者: [Peña-Miller R]
通讯作者: Peña-Miller R
DOI: 10.1371/journal.pcbi.1005269
发表时间: 2016-12
期刊: PLoS computational biology
影响因子: 4.3
作者: [Gudelj I, Kinnersley M, Rashkov P, Schmidt K, Rosenzweig F]
通讯作者: Rosenzweig F
Biophysical mechanisms that maintain biodiversity through trade-offs.
通过权衡维持生物多样性的生物物理机制。
DOI: 10.1038/ncomms7278
发表时间: 2015
期刊: Nature communications
影响因子: 16.6
作者: [Meyer JR]
通讯作者: Meyer JR
DOI: 10.1371/journal.pbio.1002104
发表时间: 2015-04
期刊: PLoS biology
影响因子: 9.8
作者: [Fuentes-Hernandez A, Plucain J, Gori F, Pena-Miller R, Reding C, Jansen G, Schulenburg H, Gudelj I, Beardmore R]
通讯作者: Beardmore R
Global Meteorological Simulator (GMS): For plant health and disease
  • 批准号:
    BB/W019965/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $89.21万
  • 财政年份:
    2022
  • 负责人:
    Ivana Gudelj
  • 依托单位:
BBSRC-NSF/BIO - The impact of public versus private metabolism on the stability of microbial communities within natural hosts
  • 批准号:
    BB/T015985/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $57.36万
  • 财政年份:
    2020
  • 负责人:
    Ivana Gudelj
  • 依托单位:
Transmission and coevolutionary dynamics drive the evolution of generalist and specialist viruses
  • 批准号:
    BB/J010340/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $33.12万
  • 财政年份:
    2011
  • 负责人:
    Ivana Gudelj
  • 依托单位:
Doctoral Training Grant (DTG) to provide funding for 1 PhD Studentship
  • 批准号:
    NE/H524730/1
  • 项目类别:
    Training Grant
  • 资助金额:
    $9.83万
  • 财政年份:
    2009
  • 负责人:
    Ivana Gudelj
  • 依托单位:
国内基金
海外基金
Scalable Learning and Optimization: High-dimensional Models and Online Decision-Making Strategies for Big Data Analysis
河北南部地区灰霾的来源和形成机制研究
  • 批准号:
    41105105
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    25.0万元
  • 批准年份:
    2011
  • 负责人:
    王丽涛
  • 依托单位:
保险风险模型、投资组合及相关课题研究
  • 批准号:
    10971157
  • 项目类别:
    面上项目
  • 资助金额:
    24.0万元
  • 批准年份:
    2009
  • 负责人:
    胡亦钧
  • 依托单位:
RKTG对ERK信号通路的调控和肿瘤生成的影响