Differential Changes in Cortical Tumour Necrosis Factor Signalling in Mood Disorders and Schizophrenia
Differential Changes in Cortical Tumour Necrosis Factor Signalling in Mood Disorders and Schizophrenia
批准号:
nhmrc : 1066144
负责人:
A/Pr Elizabeth Scarr
金额:
$42.81万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2014
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2014-01-01 至 2016-12-31
中文摘要
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英文摘要
Changes in inflammation-related pathways contribute to the symptoms of psychiatric disorders and tumour necrosis factor ? (TNF) is a protein central to regulating theses pathways. We have now shown that changes in pathways regulated by TNF are present in the brains of people with schizophrenia and mood disorders. This means that the symptoms experienced by those with the different disorders may be linked to differential changes in TNF-regulated pathways in the brain.
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海外基金