Understanding the pathology of Muscarinic Receptor Deficit Schizophrenia: A biochemically defined form of the disorder.

了解毒蕈碱受体缺陷型精神分裂症的病理学：该疾病的一种生化定义形式。

• 批准号: nhmrc : 566967
• 负责人: A/Pr Elizabeth Scarr
• 金额: $ 30.13万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/understanding-pathology-muscarinic-form-disorder/97464
• 关键词: Understanding; pathology; Muscarinic; Receptor; Deficit

Schizophrenia is a group of disorders with similar symptoms and no way of distinguishing the different disorders. In our brain collection 25% of the subjects with schizophrenia have a particular chemical deficit. Screening gene expression in people with schizophrenia, with and without this deficit will give a global picture of chemical differences between the groups. Understanding the differences between sub-groups of people with schizophrenia will aid the development of better drugs for them.

精神分裂症是一组具有相似症状的疾病，无法区分不同的疾病。在我们收集的大脑中，25%的精神分裂症患者有一种特殊的化学缺陷。筛选有和没有这种缺陷的精神分裂症患者的基因表达将给出各组之间化学差异的全局图。了解精神分裂症患者亚群之间的差异将有助于为他们开发更好的药物。