A Breakdown of Cortical Homeostasis in Depression: A Focus on the Anterior Cingulate

20%的澳大利亚人患有重度抑郁症。重度抑郁症的一些症状是由于人类大脑功能障碍，特别是大脑皮层功能障碍引起的。我们的研究表明，患有情绪障碍的人的前扣带皮层存在生化变化。我们现在将扩展我们的研究，以证明在抑郁症患者的前扣带皮层中，神经递质和神经炎症通路之间的平衡被破坏了。

Major depressive disorders affect 20% of the Australian population. Some symptoms of major depressive disorders arise because of a dysfunction of the human brain, particularly the cortex. Our studies show there are biochemical changes in the anterior cingulate cortex in people with mood disorders. We will now extend our studies to show there is a breakdown in the balance between neurotransmitter and neuroinflammation pathways in the anterior cingulate cortex in major depressive disorders.