A multi-centre double-blind RCT on community-acquired pneumonia in Indigenous children and a developing country: Improving clinical outcomes and identifying systemic biomarkers

针对土著儿童和发展中国家社区获得性肺炎的多中心双盲随机对照试验：改善临床结果并确定全身生物标志物

• 批准号: nhmrc : 1098443
• 负责人: A/Pr Tsin Yeo
• 金额: $ 149.9万
• 依托单位: Menzies School of Health Research
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 2022-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/multi-centre-double-systemic-biomarkers/662382
• 关键词: multi; centre; double; blind; RCT

Young children of Indigenous communities and developing countries are often hospitalised for pneumonia and have high risk of subsequent chronic disease. Our international study will determine if a longer duration of antibiotics (compared to shorter duration) improves the short and long term clinical outcomes of children hospitalised for pneumonia. We will look for unique markers that may predict those who will develop chronic lung disease. Our study will influence future guidelines on pneumonia.

土著社区和发展中国家的幼儿往往因肺炎住院，随后患慢性病的风险很高。我们的国际研究将确定较长时间的抗生素（与较短时间相比）是否能改善肺炎住院儿童的短期和长期临床结果。我们将寻找独特的标记，可以预测那些将发展为慢性肺病的人。我们的研究将影响未来的肺炎指南。