DETERMINANTS OF BASAL FFA FLUX

比较非裔美国人、高加索人、瘦肉型和肥胖型以及男性和女性的FFA流量。以确定在被认为具有病理生理学意义的情况下是否存在血浆FFA递送增加的情况，并检查一旦FFA离开血浆并进入肌脂池后的命运。在纽约圣卢克斯-罗斯福的Jeanine Albu医生和密苏里州圣路易斯华盛顿大学的Samuel Klein医生的合作下，这些研究完成了。在罗切斯特的梅奥诊所，我们已经完成了对高加索人的所有研究，并研究了一名非裔美国女性和11名非裔美国男性。样品的最终分析目前正在进行中。我们似乎已经完成了这项研究，尽管尚未对所有样本进行最终分析。在明尼苏达州罗切斯特市对所有高加索志愿者进行了研究。许多非裔美国志愿者也在明尼苏达州的罗切斯特进行了研究，然而，我们与密歇根州圣路易斯和纽约的研究人员合作完成了拟议的研究。

To compare FFA flux in African-American, Caucasian, lean and obese, and men and women. To determine whether increased plasma FFA delivery is present in conditions which are thought to be pathophysiologically important and examine a fate of FFA once they have exited plasma and entered muscle lipid pools. In collaboration with Doctors Jeanine Albu of St. Lukes-Roosevelt, New York, NY and Samuel Klein of Washington University, St. Louis, MO, these studies are completed. At Mayo Clinic in Rochester we have completed all the studies of Caucasians and have studied one African-American woman and 11 African-American men. Final analysis of samples is currently underway. We appear to have completed this study, although final analysis have not been performed on all samples. All of the Caucasian volunteers proposed for this protocol were studied in Rochester, MN. A number of the African-American volunteers were also studied in Rochester, MN, however, we collaborated with the investigators in St. Louis, MI, and New York, NY, to complete the proposed studies.