REGIONAL FATTY ACID METABOLISM IN HUMANS

本研究的目的是确定膳食中所含的脂肪是如何被吸收并储存在超重女性的身体脂肪中的，无论是否患有糖尿病，在治疗之前和之后，预期会导致体重减轻和改善与肥胖相关的健康问题。对数据的分析表明，我们已经解决了我们的假设，并撰写了一篇论文并提交出版。 由于芬氟拉明/芬特明引起的心脏瓣膜疾病的问题，我们从这些药物中撤出了所有志愿者。 对每名志愿者进行密切随访，以评估瓣膜异常是否进展或消退。本报告期间无患者活动。 在生物医学质谱核心实验室继续进行样品分析。

The purpose of this study is to determine how fat contained in a meal is absorbed and stored in body fat in overweight women with and without diabetes before and after treatment expected to result in weight loss and improvement of health problems related to obesity. Analysis of the data indicated we had addressed our hypothesis and a paper has been written and submitted for publication. Because of the problems with cardiac valvular disease induced by fenfluramine/phentermine, we withdrew all volunteers from these medications. Each volunteer is being followed closely to assess whether there is progression or regression of the valvular abnormalities. There was no patient activity during this reporting period. Sample analysis was continued in the Biomedical Mass Spectrometry Core Laboratory.