GENETIC PREDISPOSITION IN HYPERTENSION AND DIABETIC NEPHROPATHY

高血压和糖尿病肾病的遗传倾向

• 批准号: 6121338
• 负责人: NORMAN K HOLLENBERG
• 金额: $ 5.27万
• 依托单位: BRIGHAM AND WOMEN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6121338
• 关键词: clinical research; diabetic nephropathy; disease /disorder proneness /risk; family genetics; genetic susceptibility; human subject; kidney function; pathologic process; renal hypertension

The purpose of this study is to advance the understanding of the causes of kidney disease in diabetes. This study will try to determine the cause of mild abnormalities in kidney fuction prior to the development of significant abnormalities and high blood pressure in people with diabetes. This knowledge may help make it possible to prevent or modify the development of kidney disease in the early phases of diabetes when and if the high risk patients can be identified.

本研究的目的是促进对糖尿病肾病病因的认识。这项研究将试图确定糖尿病患者在发生严重异常和高血压之前肾功能轻度异常的原因。这一知识可能有助于在糖尿病早期阶段预防或改变肾脏疾病的发展，如果能够识别高危患者的话。