TESTING OF DENTAL RESTORATIVE MATERIAL

牙科修复材料的测试

• 批准号: 6238523
• 负责人: HENRY L YOUNG
• 金额: $ 5.77万
• 依托单位: MEHARRY MEDICAL COLLEGE
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-08-01 至 1998-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6238523
• 关键词: biomaterial evaluation; composite resins; dental material wear; dental materials; human subject

The long term goal of the project is to provide clinicians with scientific information which they could use to assist in making the best selection of which restorative material they would incorporate in providing treatment options for patients. Presently, there is an increase in usage of composite resins as posterior restorations. To date most research efforts have been devoted to improving the wear resistance of composite resin restorations. Little effort has been made to determine possible wear of the cusp opposing the composite restoration. The specific aim of this proposed study is to evaluate the effect of a series of five composite in lay systems, of varying composition and particle size, on the wear resistance of human enamel. This project will consist of two phases. Phase I will consist of an in vitro study and Phase II an in vivo study. In Phase I caries free extracted human molars are selected for the study. The specimen is prepared and an composite in lay fabricated and cemented. The specimen is mounted and inserted into a wear test apparatus. This wear device can be used for the critical evaluation of all restorative materials and in fact has been used in conjunction with past studies as well as implants. The teeth selected as the antagonist will consist of the buccal cusp of mandibular first premolars. Small acrylic resin beads are used to serve as the food bolus thereby generating as well as the restored surface of the molar will be evaluated using an image-analyzing system. The surface area for wear facets is calculated automatically by a computer at a magnification of x5O. The values of the surface area for wear facets will be statistically analyzed by a one-factor analysis of variance (P-1 <05). Multiple comparison among respective composite resins will be made with the Fisher test at a 95% level of confidence. In Phase II one hundred composite inlays will be inserted into Class I and II cavity preparations in vivo. All restorations will be inserted over a ninety day period by two clinicians following a strict clinical protocol. The antagonist cusp and the posterior restoration will be evaluated at baseline 3 mos., 6 mos., 12 mos., 24 mos., 36 mos. and 48 mos. By indirect evaluation using epoxy resin models, the wear of the opposing cusp as well as the composite restoration will be determined using an image analyzing system. The same protocol for analysis of data used in Phase l will be repeated for Phase Il.

该项目的长期目标是为临床医生提供科学的 他们可以用来帮助做出最佳选择的信息 在提供治疗时， 患者的选择。目前，使用 复合树脂作为后牙充填物。迄今为止， 一直致力于提高复合树脂的耐磨性 道歉 几乎没有努力确定可能的磨损， 尖瓣与复合修复体相对。其具体目的是 拟议的研究是评估一系列的五个复合材料的效果， 不同成分和粒度的涂层系统， 人牙釉质的抵抗力。该项目将包括两个阶段。 I期包括体外研究，II期包括体内研究。 在第一阶段中，选择无龋拔除的人磨牙进行研究。 制备试样，并在层内制造复合材料并进行粘结。 将试样安装并插入磨损试验装置中。这种磨损 设备可用于所有修复的关键评价 材料，事实上已与过去的研究结合使用， 以及植入物。选择作为拮抗剂的牙齿将包括 下颌第一前磨牙的颊侧尖。丙烯酸树脂小珠 用来作为食物团，从而产生以及恢复 将使用图像分析系统评估磨牙的表面。 磨损面的表面积由计算机自动计算 在50倍的放大率下。磨损面的表面积值 将通过单因素方差分析（P-1）进行统计分析 <05）。将对各种复合树脂进行多重比较 在95%的置信水平下进行Fisher检验。在第二阶段，100 将复合嵌体插入I类和II类洞制备物中 in vivo.在九十天的时间里，所有的解释都将由两个 临床医生遵循严格的临床协议。拮抗瓣尖和 将在基线3个月时评价后部修复，6个月，12 莫斯，24个月，36个月和48个月。通过使用环氧树脂的间接评价 树脂模型、对侧瓣尖磨损以及复合材料 将使用图像分析系统来确定恢复。相同的 I期使用的数据分析方案将重复用于I期 IL.