DEVELOPMENT OF FLURBIPROFEN AS A SELECTIVE PROBE OF CYP2C9

药物代谢是体内参与药物代谢的重要过程 一些化合物的消除和活化 随之而来的毒性。该项目旨在 研究氟比洛芬作为选择性探针的潜在用途 CYP2C9&将其整合到已经开发的 5种药物鸡尾酒。我们的目标是能够广泛使用它 人群研究以评估细胞色素P450 2 C9在致病机制中的作用 疾病的预后。

Drug metabolism is an important process in the body involved in drug elimination as well as in activation of some compounds & the consequential development of toxicities. This project is designed to investigate the potential use of Flubiprofen as a selective probe of CYP2C9 & the possibility of incorporating it into an already developed 5 drug cocktail. The objective is to be able to use it in large population studies to assess the role of CYP2C9 in the pathogenesis or prognosis of diseases.