DEVELOPMENT OF FLURBIPROFEN AS A SELECTIVE PROBE OF CYP2C9

药物代谢是药物参与的机体重要过程 消除以及在某些化合物的激活和相应的 发展毒性。该项目旨在调查 氟比洛芬作为CYP2C9选择性探针的潜在用途 将其纳入已经开发的5种药物鸡尾酒的可能性。 目标是能够在大规模人群研究中使用它， 评估CYP2C9在疾病发病机制或预后中的作用。

Drug metabolism is an important process in the body involved in drug elimination as well as in activation of some compounds & the consequential development of toxicities. This project is designed to investigate the potential use of Flubiprofen as a selective probe of CYP2C9 & the possibility of incorporating it into an already developed 5 drug cocktail. The objective is to be able to use it in large population studies to assess the role of CYP2C9 in the pathogenesis or prognosis of diseases.