Do changes in HCN channels function cause epilepsy?
Do changes in HCN channels function cause epilepsy?
批准号:
nhmrc : 1009142
负责人:
A/Pr Christopher Reid
金额:
$25.75万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2011
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2011-01-01 至 2013-12-31
中文摘要
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英文摘要
About 100 000 people suffer from epilepsy in Australia with about one third poorly controlled with current anti-epileptic drugs. It is important to continue to develop novel modes of treatment for this debilitating disease. This project investigates an ion channel, known as HCN that is thought to be involved in making a brain epileptic. Understanding how changes in HCN channels make nerve cells and nerve networks more excitable will help us develop better strategies for designing drugs.
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HCN4 channels: a novel antiepileptic target
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批准号:nhmrc : GNT1143101
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项目类别:Project Grants
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资助金额:$56.87万
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财政年份:2018
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负责人:A/Pr Christopher Reid
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依托单位:
HCN4 channels: a novel antiepileptic target
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批准号:nhmrc : 1143101
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项目类别:Project Grants
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资助金额:$38.45万
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财政年份:2018
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负责人:A/Pr Christopher Reid
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依托单位:
Human Epilepsy: Understanding biology to improve outcomes
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批准号:nhmrc : GNT1091593
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项目类别:Programs
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资助金额:$1611.03万
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财政年份:2016
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负责人:A/Pr Christopher Reid
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依托单位:
Human Epilepsy: Understanding biology to improve outcomes
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批准号:nhmrc : 1091593
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项目类别:Program Grants
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资助金额:$1110.75万
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财政年份:2016
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负责人:A/Pr Christopher Reid
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依托单位:
Glucose homeostasis in epilepsy
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批准号:nhmrc : 1050161
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项目类别:Project Grants
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资助金额:$20.84万
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财政年份:2013
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负责人:A/Pr Christopher Reid
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依托单位:
Changing the course of epileptogenesis
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批准号:nhmrc : 628520
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项目类别:NHMRC Project Grants
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资助金额:$35.64万
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财政年份:2010
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负责人:A/Pr Christopher Reid
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依托单位:
Altered HCN channel expression and function in acquired epilepsy
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批准号:nhmrc : 454655
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项目类别:NHMRC Project Grants
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资助金额:$18.66万
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财政年份:2007
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负责人:A/Pr Christopher Reid
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依托单位:
NPY suppresses seizures and modulates thalamocortical activity in animal models of generalized epilepsy
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批准号:nhmrc : 400106
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项目类别:NHMRC Project Grants
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资助金额:$25.74万
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财政年份:2006
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负责人:A/Pr Christopher Reid
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依托单位:
Mechanisms underlying short- and long-term plasticity at the mossy fibre -> CA3 synapse in the hippocampus
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批准号:nhmrc : 236801
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项目类别:NHMRC Project Grants
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资助金额:$18.19万
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财政年份:2003
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负责人:A/Pr Christopher Reid
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依托单位:
Synaptic Plasticity in the Central Nervous System
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批准号:nhmrc : 237098
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项目类别:Early Career Fellowships
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资助金额:$3.82万
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财政年份:2002
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负责人:A/Pr Christopher Reid
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依托单位:
国内基金
海外基金
中国的城市变化及其自组织的空间动力学
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批准号:40335051
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项目类别:重点项目
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资助金额:90.0万元
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批准年份:2003
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负责人:周一星
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依托单位: