Glucose homeostasis in epilepsy

癫痫中的血糖稳态

• 批准号: nhmrc : 1050161
• 负责人: A/Pr Christopher Reid
• 金额: $ 20.84万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/glucose-homeostasis-epilepsy/112140
• 关键词: Glucose; homeostasis; epilepsy

Epilepsy is often poorly controlled by medication and dietary measures can be taken that reduce occurrence of epileptic seizures. Glucose control is impacted by diet and also mutations in the genes that move glucose around the body are known to cause epilepsy. Here we will be studying how the genetic and dietary control of glucose levels impacts brain function to increase seizures and to potentially reveal novel therapies.

癫痫往往难以通过药物控制，可采取饮食措施减少癫痫发作的发生。血糖控制受到饮食的影响，而且在体内移动葡萄糖的基因突变也会导致癫痫。在这里，我们将研究葡萄糖水平的遗传和饮食控制如何影响大脑功能，从而增加癫痫发作，并潜在地揭示新的治疗方法。