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Do the Developmental vitamin D-deficiency and maternal immune activation animal models of schizophrenia have convergent early pathways ?

Do the Developmental vitamin D-deficiency and maternal immune activation animal models of schizophrenia have convergent early pathways ?
精神分裂症的发育性维生素 D 缺乏和母体免疫激活动物模型是否具有趋同的早期途径?
批准号:
nhmrc : 1057883
负责人:
Prof Darryl Eyles
金额:
$44.65万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2014
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2014-01-01 至 2017-12-31

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中文摘要
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英文摘要
The etiology of schizophrenia is unknown but it is generally considered to have a neurodevelopmental basis and involve altered dopamine signaling. Using two distinct developmental animal models of schizophrenia we have shown convergent gestational abnormalities in how dopamine systems develop. This is possibly a convergent early etiological mechanism in schizophrenia.
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会议论文
Maternal vitamin D supplementation in a maternal immune activation model of schizophrenia: mechanisms of prevention
  • 批准号:
    nhmrc : GNT1124721
  • 项目类别:
    Project Grants
  • 资助金额:
    $52.34万
  • 财政年份:
    2017
  • 负责人:
    Prof Darryl Eyles
  • 依托单位:
Maternal vitamin D supplementation in a maternal immune activation model of schizophrenia: mechanisms of prevention
  • 批准号:
    nhmrc : 1124721
  • 项目类别:
    Project Grants
  • 资助金额:
    $35.78万
  • 财政年份:
    2017
  • 负责人:
    Prof Darryl Eyles
  • 依托单位:
A new animal model of the prodrome in schizophrenia. Enhanced Dopamine in Prodromal Schizophrenia (EDiPs)
  • 批准号:
    nhmrc : GNT1124724
  • 项目类别:
    Project Grants
  • 资助金额:
    $57.2万
  • 财政年份:
    2017
  • 负责人:
    Prof Darryl Eyles
  • 依托单位:
A new animal model of the prodrome in schizophrenia. Enhanced Dopamine in Prodromal Schizophrenia (EDiPs)
  • 批准号:
    nhmrc : 1124724
  • 项目类别:
    Project Grants
  • 资助金额:
    $39.11万
  • 财政年份:
    2017
  • 负责人:
    Prof Darryl Eyles
  • 依托单位:
海外基金