PHARMACOKINETICS OF 18F SETOPERONE IN SEASONAL AFFECTIVE DISORDER (SAD)

1)要确定18F-setopone PET扫描是否会定义差异 季节性情感性患者中5HT2受体的占用和显示 与正常相比，志愿者的精神障碍程度是否 情感障碍将与这些PET有定量的关系 扫描结果。2.)以确定患者在临床上是否对 治疗将在他们的PET扫描结果中显示正常化，并且 与他们治疗前的研究相比有很大的变化。

1.) To determine if 18F-setoperone PET scanning will define a difference in 5HT2 receptor occupancy and display in patients with seasonal affective disorder when compared with normal, volunteers and whether the extent of the affective disorder will bear a quantatative relationship th these PET scan findings. 2.) To determine if patients responding clinically to therapy will manifest a normalization in their PET scan findings, and a significant change from their pre-therapy study.