SONOPHORETIC TRANSDERMAL GLUCOSE EXTRACTION

评估应用低频超声是否提取葡萄糖 穿过人体皮肤 为了找出最少需要的时间， 通过超声波促渗法在皮肤上提取足够量的葡萄糖。 到 评估以这种方式提取的葡萄糖的量是否与 与患者的血糖浓度有关。 为了评估一个 血糖水平的动态变化导致可检测到的 超声提取葡萄糖的量并考察时间 这两个变化之间的差距。 评估患者依从性相关 与使用低频超声促渗进行非侵入性治疗相关的问题 血糖测量。

To assess whether application of low frequency ultrasound extracts glucose across the human skin in vivo. To find out the minimum time required to extract sufficient amount of glucose across the skin by sonophoresis. To assess whether the amount of glucose extracted in this manner correlates with the blood glucose concentrations of patients. To assess whether a dynamic change in blood glucose level results in a detectable change in the amount of glucose extracted by sonophoresis and investigate the time lag between these two changes. To assess patient compliance related issues associated with using low-frequency sonophoresis for non-invasive blood-glucose measurements.