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MULTIPHOTON IMAGING OF NEMATODE NEURONAL GROWTH CONES

MULTIPHOTON IMAGING OF NEMATODE NEURONAL GROWTH CONES
线虫神经元生长锥的多光子成像
批准号:
6278475
负责人:
MICHAEL J BASTIANI
金额:
$2.74万
依托单位国家:
美国
项目类别:
财政年份:
1998
资助国家:
美国
项目状态:
已结题
起止时间:
1998-07-01 至 2000-06-30

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中文摘要
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英文摘要
We want to characterize DD and UD growth cone behavior during embryonic and post embryonic (LI) development of the nematode nervous system. We plan to use multiphoton confocal microscopy and 41) software to observe GFP expressing UD and DD neurons in wild-type and mutant nematodes to better understand the role played by specific molecules in growth cone pathfinding and target recognition. Initial studies will be performed using confocal microscopy. However, it appears likely we will need the multiphoton scope to maintain viability during long term fiequent collection of data sets.
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A comprehensive RNAi based screen for genes effecting neural degeneration in C. e
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  • 项目类别:
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