MICRO BLOOD VESSEL VASOCONSTRICTION DURING BRAIN INJURY

我们正在研究大动脉血管收缩的本质 来自经受全脑缺血的大鼠脑（实验临床 死亡）。 HVEM用于可视化免疫金定位， 特异性表面膜相关整合素和免疫球蛋白 三个维度的感受器 HVEM的使用至关重要， 对于评估受体定位很重要， 使用SEM和/或薄切片TEM技术的组合得出结论。 博士 Lossinsky今年多次访问了资源。 立体图像 在免疫金标记的脑肿瘤囊泡的HVEM上记录 并创建了一个测试Sterecon重建。 Lossinsky，A.S.，K.F. 巴特尔河Pluta，M. J. Mossakowski和H. M.维斯涅夫斯基 （一九九七年） 细胞间粘附分子-1（ICAM-1/CD54）在人乳腺癌中的表达上调 发育和肿瘤中的泡状管状结构（VTS） 血脑屏障 J. Histochem. 细胞化学 (in Press）。

We are studying the nature of vasoconstriction in large arterioles from rat brains subjected to global ischemia (experimental clinical death). The HVEM is used to visualize the immunogold localization of specific surface membrane-associated integrin and immunoglobulin receptors in three dimensions. The use of the HVEM is critically important for evaluating receptor localization which may not be conclusive using combined SEM and/or thin section TEM techniques. Dr. Lossinsky visited the Resource several times this year. Stereo images were recorded on the HVEM of immunogold labeled brain tumor vesicles and a test Sterecon reconstruction was created. Lossinsky, A.S., K.F. Buttle, R. Pluta, M. J. Mossakowski and H.M. Wisniewski. (1997) Intercellular adhesion molecule-1 (ICAM-1/CD54) up-regulation in vesiculo-tubular structures (VTS) in the developmental and neoplastic blood-brain barrier. J. Histochem. Cytochem. (in press).