COHERENT PHENOMENA IN ULTRAFAST BIOLOGICAL PROCESSES

超快生物过程中的连贯现象

• 批准号: 6281048
• 负责人: ROBIN Main HOCHSTRASSER
• 金额: $ 1.07万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-08-01 至 1999-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6281048
• 关键词: biological products; biomaterials; biomedical equipment development; biomedical resource; proteins; technology /technique

An important question is whether the coherence introduced by optical excitation in the initial step of a light driven reaction is maintained during the primary process or not: Does the dynamics of the initially formed wavepacket on the reactive surface involve coherent motion? The observations of coherent wavepacket propagation provides an additional probe of the nature of the potential energy surface upon which the primary dynamical processes are occurring. It was decided to build a 16 fs time resolution pump/probe spectrometer capable of examining coherent propagation of wavepackets in large molecules incorporating vibrational excitations as large as ca. 1000 cm-1. This research is aimed at understanding wavepacket propagation processes and hence will focus on model systems initially, particularly systems undergoing electron transfer or isomerism. We would ask what is the participation of coherence in such processes. The reaction center is also a natural objective of this research. These experiments address how significant are coherent vibrational phenomena in ultrafast processes. However they are also expected to explore new ways of measuring and simulating coherent effects in proteins. This is a very new area of research and work on model compounds is being pursued (such as in porphyrin assemblies).

一个重要的问题是， 在光驱动反应的初始步骤中的光激发是 在主要过程中维持与否： 反应表面上最初形成的波包包括 相干运动？ 相干波包传播的观测 提供了一个额外的探索性质的势能 主要动力学过程发生的表面。 它 决定建立一个16 fs时间分辨率的泵浦/探测光谱仪 能够检查波包的相干传播， 分子纳入振动激发大约。 1000 cm-1. 这项研究的目的是了解波包传播 过程，因此将集中在模型系统最初， 特别是经历电子转移或异构的体系。 我们 我会问，什么是一致性在这些进程中的参与。 反应中心也是本研究的自然目标。 这些实验说明了相干振动 超快过程中的现象。 然而，他们也被期望 探索测量和模拟相干效应的新方法， proteins. 这是一个非常新的研究领域， 化合物（如卟啉组装体）。