TRACKING OF BONE MASS DURING CHILDHOOD AND ADOLESCENCE

跟踪儿童期和青少年期的骨量

• 批准号: 6295055
• 负责人: Heidi J Kalkwarf
• 金额: $ 3.1万
• 依托单位: CINCINNATI CHILDRENS HOSP MED CTR
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6295055
• 关键词: adolescence (12-20); bone density; clinical research; female; human subject; longitudinal human study; middle childhood (6-11); normal ossification; photon absorptiometry; preschool child (1-5)

The objective of this study is to assess tracking of bone mass during childhood and adolescence. Specifically, we will estimate the degree of tracking over 1 and 2 year intervals in girls between 3 and 17 years of age. Annual measurements of bone mineral content and density will be measured by dual energy x-ray absorptiometry for three years. A total of 245 girls have been enrolled in the study, and 167 have completed their second annual measurement. We are also evaluating the comparability of bone density measurements obtained by peripheral Quantitated Computed Tomography (pQCT) to those obtained by DEXA. This will allow us to determine which technology to use in future studies of bone mineralization in children.

这项研究的目的是评估儿童和青春期骨量的跟踪。具体地说，我们将评估3至17岁女孩在1到2年的间隔时间内跟踪的程度。骨矿含量和密度的年度测量将用双能X射线吸收法测量，为期三年。共有245名女孩参加了这项研究，其中167人完成了第二次年度测量。我们还在评估外周定量计算机断层扫描(PQCT)获得的骨密度测量结果与DEXA获得的结果的可比性。这将使我们能够确定在未来的儿童骨矿化研究中使用哪种技术。