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CIRCADIAN AND GENDER DIFFERENCES IN THE QT DISPERSION

CIRCADIAN AND GENDER DIFFERENCES IN THE QT DISPERSION
QT 离散度的昼夜节律和性别差异
批准号：
6114052
负责人：
Alan H Kadish
金额：
$2.05万
依托单位：
NORTHWESTERN UNIVERSITY AT CHICAGO
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6114052
关键词：
circadian rhythms clinical research electrocardiography female gender difference heart electrical activity human subject male

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中文摘要
翻译
儿童权利委员会以前的工作证实，QT间期存在性别差异，女性的QT间期平均比男性长10毫秒。这种差异不能用自主神经张力的不同或月经周期的变化来解释。本研究的目的是在有和没有潜在心脏病的患者中，用标准12导联心电图和体表标测的QT间期来测量心室复极离散度的性别和昼夜差异。
英文摘要
Previous work performed in the CRC has confirmed that there is a gender difference in the QT interval with a mean 10ms longer QT interval in women than in men. This difference is not explained by difference in autonomic tone or by menstural cycle variation. The purpose of this study is to examine gender and circadian differences in the dispersion of ventricular repolarization as measured by the QT interval, as measured on the standard 12 lead ECG and by body surface mapping in patients with and without underlying heart disease.
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