CALORIC RESTRICTION/PHYSICAL EXERCISE ON ENERGY METABOLISM--SEX DIFFERENCES

热量限制/体育锻炼对能量代谢的影响——性别差异

• 批准号: 6305684
• 负责人: VERNON R YOUNG
• 金额: $ 4.04万
• 依托单位: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-12-01 至 2001-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6305684
• 关键词: basal metabolism; bioenergetics; body composition; caloric dietary content; calorimetry; clinical research; dietary restriction; exercise; gender difference; human subject; nutrient intake activity; nutrition related tag; radiotracer

To compare and contrast 1) changes in body composition, kinetics of major energy-yielding substrate metabolism in men and women, under resting conditions and during and following moderate exercise, during a three-week period of hypocaloric feeding. 2) kinetic and metabolic studies will include feasible and novel 24-hour stable isotope tracer-indirect calorimetry protocols, 3) explore the parameters outlined above under conditions of a balanced reduction in energy intake in comparison with a high protein/energy (lipid) dense hypocaloric diet in women and men.

比较和对比1）在低热量喂养的三周期间，男性和女性在静息条件下以及在适度运动期间和之后的身体组成、主要能量产生底物代谢动力学的变化。 2)动力学和代谢研究将包括可行的和新颖的24小时稳定同位素示踪剂-间接热量测定法方案，3）与高蛋白/能量（脂质）密集的低热量饮食相比，在平衡减少能量摄入的条件下探索上述参数。