课题基金 / 基金详情

TOXICOLOGICAL EVALUATIONS OF POTENTIAL MEDICATIONS TO

TOXICOLOGICAL EVALUATIONS OF POTENTIAL MEDICATIONS TO
潜在药物的毒理学评价
批准号：
6359422
负责人：
BARRY S LEVINE
金额：
$47.03万
依托单位：
UNIVERSITY OF ILLINOIS AT CHICAGO
依托单位国家：
美国
项目类别：
财政年份：
1999
资助国家：
美国
项目状态：
已结题
起止时间：
1999-09-30 至 2003-09-29
来源：
https://reporter.nih.gov/project-details/6359422
关键词：
Primates Rodentias dogs dosage drug adverse effect drug screening /evaluation gastrointestinal motility /pressure kidney function toxicology

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中文摘要
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英文摘要
The contract will include evaluations of the compound's acute and repeat dose toxicity in rodents, dogs and/or primates. In addition, studies to determine the compound's effect on GI motility and renal function, and the compound's genotoxicity may also be conducted. The evaluations of safety/toxicity of drugs will be conducted under the GLP regulations of the FDA.
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